A cross-sectional study of lung volume development in pectus excavatum patients: estimating the total lung volume from chest computed tomograph using 3-dimensional volumetric reconstruction

Abstract Background/Purpose This study quantified the lung volume development of pectus excavatum (PE) patients using chest computed tomography (CT) 3-dimensional volumetric reconstructions. The technique permits current and retrospective analyses of data from different institutions. Patients and Me...

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Published in:Journal of pediatric surgery 2010-12, Vol.45 (12), p.2322-2327
Main Authors: Zeng, Qi, Lai, Jin-Yao, Wang, Chao-Jan, Cheng, Hsiao-Yang, Chu, Chih-Chun, Chang, Chee-Jen, Chiu, Pin-Hsiu, Chen, Zung-Chung, Chang, Pei-Yeh
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Anthropometry
Body Height
Child
Child, Preschool
Cross-Sectional Studies
Female
Funnel Chest - diagnostic imaging
Funnel Chest - pathology
Humans
Imaging, Three-Dimensional
Lung - diagnostic imaging
Lung - pathology
Lung volume
Lung Volume Measurements
Male
Organ Size
Pectus excavatum
Pectus index
Pediatrics
Radiography
Retrospective Studies
Surgery
Three-dimensional computed tomography
Young Adult
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Summary:Abstract Background/Purpose This study quantified the lung volume development of pectus excavatum (PE) patients using chest computed tomography (CT) 3-dimensional volumetric reconstructions. The technique permits current and retrospective analyses of data from different institutions. Patients and Methods We analyzed the records of PE patients who underwent chest CT preoperatively between 2005 and 2009 at 3 institutions. All patients were Chinese. A window of −992 to −198 Hounsfield units was chosen for calculating the CT total lung volume (TLV). The data were compared with the data for 73 microtia and other chest-wall tumor patients studied during the same period as a control group. Results In total, 377 PE patients with Haller pectus index (PI) of at least 3.2 were identified for this study. Compared with the reported TLV data for 1050 healthy children and our control group, we found little evidence of a decreased TLV in PE patients at any age for either sex. The mean PI did not change significantly between the ages of 3 and 27 years. The PI was inversely correlated with the TLV ( P < .001). Conclusion Our cross-sectional study provides evidence that the TLV of PE patients is within the reference range in children and adolescents.
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2010.08.023