Loading…
Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer
Background: Endoscopic resection of early gastric cancer is a relatively new and attractive treatment, but occasionally fails to remove all cancer lesions completely. This study aimed to elucidate clinicopathological factors that could be helpful in predicting residual tumour in the surgical specime...
Saved in:
| Published in: | British journal of surgery 2011-01, Vol.98 (1), p.73-78 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c4554-d4688262be462a242f979eba55b89507dfd890dd774cdc0d7db10fe7a3ea5403 |
|---|---|
| cites | |
| container_end_page | 78 |
| container_issue | 1 |
| container_start_page | 73 |
| container_title | British journal of surgery |
| container_volume | 98 |
| creator | Jung, H. Bae, J. M. Choi, M. G. Noh, J. H. Sohn, T. S. Kim, S. |
| description | Background:
Endoscopic resection of early gastric cancer is a relatively new and attractive treatment, but occasionally fails to remove all cancer lesions completely. This study aimed to elucidate clinicopathological factors that could be helpful in predicting residual tumour in the surgical specimen after incomplete endoscopic submucosal dissection (ESD).
Methods:
Patients who underwent gastrectomy because of incomplete ESD between August 2004 and August 2008 were analysed. Clinicopathological characteristics were reviewed retrospectively from prospectively collected medical records. Patients were classified into groups with and without residual tumour. Pathology results following gastrectomy were compared with those of incomplete ESD.
Results:
A total of 118 patients were included. The incidence of residual tumour in the surgical specimen was 24·6 per cent after incomplete ESD. Elevated/flat‐type cancers, large tumours (at least 2 cm) and those limited to the mucosa had significantly higher incomplete ESD rates. Cancer limited to the mucosa and the presence of tumour in the lateral margin were associated with residual tumour in the surgical specimen (both P = 0·001).
Conclusion:
Radical gastrectomy should be performed if pathological examination reveals a positive lateral resection margin after ESD. Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Incomplete endoscopic resection necessitates surgery |
| doi_str_mv | 10.1002/bjs.7274 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_816528931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>816528931</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4554-d4688262be462a242f979eba55b89507dfd890dd774cdc0d7db10fe7a3ea5403</originalsourceid><addsrcrecordid>eNpF0UtLxDAQB_Agiq4P8BNIL-KpmkeTtEffjxUVdkHwEtJkKtFusyYtut_eLK56Gob5MTDzR2if4GOCMT2p3-KxpLJYQyPCBM8pEeU6GmGMZU4YZVtoO8Y3jAnDnG6iLUqWTLARmk6G8OqMbjM_9MbPINNNDyFzXWrmLfSQQWd9NH7uTBaHejYYHxO3LkYwvfNd5pvsVcc-JGB0ZyDsoo1GtxH2VnUHTa8up-c3-f3j9e356X1uCs6L3BaiLKmgNRSCalrQppIV1Jrzuqw4lraxZYWtlbIw1mArbU1wA1Iz0LzAbAcd_aydB_8xQOzVzEUDbas78ENUJRGclhUjSR6sZDoArJoHN9NhoX7_kMDhCuiYntGEdIeL_44JyjGRyeU_7tO1sPibE6yWOaiUg1rmoM7uJsv6713s4evP6_CuhGSSq-eHazV-qsYvE3KhLtg3FiOJmA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>816528931</pqid></control><display><type>article</type><title>Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer</title><source>Oxford Journals Online</source><creator>Jung, H. ; Bae, J. M. ; Choi, M. G. ; Noh, J. H. ; Sohn, T. S. ; Kim, S.</creator><creatorcontrib>Jung, H. ; Bae, J. M. ; Choi, M. G. ; Noh, J. H. ; Sohn, T. S. ; Kim, S.</creatorcontrib><description>Background:
Endoscopic resection of early gastric cancer is a relatively new and attractive treatment, but occasionally fails to remove all cancer lesions completely. This study aimed to elucidate clinicopathological factors that could be helpful in predicting residual tumour in the surgical specimen after incomplete endoscopic submucosal dissection (ESD).
Methods:
Patients who underwent gastrectomy because of incomplete ESD between August 2004 and August 2008 were analysed. Clinicopathological characteristics were reviewed retrospectively from prospectively collected medical records. Patients were classified into groups with and without residual tumour. Pathology results following gastrectomy were compared with those of incomplete ESD.
Results:
A total of 118 patients were included. The incidence of residual tumour in the surgical specimen was 24·6 per cent after incomplete ESD. Elevated/flat‐type cancers, large tumours (at least 2 cm) and those limited to the mucosa had significantly higher incomplete ESD rates. Cancer limited to the mucosa and the presence of tumour in the lateral margin were associated with residual tumour in the surgical specimen (both P = 0·001).
Conclusion:
Radical gastrectomy should be performed if pathological examination reveals a positive lateral resection margin after ESD. Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Incomplete endoscopic resection necessitates surgery</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.7274</identifier><identifier>PMID: 21136563</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Dissection - methods ; Endoscopy, Gastrointestinal - methods ; Female ; Gastric Mucosa - surgery ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroscopy - methods ; General aspects ; Humans ; Male ; Medical sciences ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm, Residual ; Prospective Studies ; Stomach Neoplasms - pathology ; Stomach Neoplasms - surgery ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Treatment Outcome ; Tumors</subject><ispartof>British journal of surgery, 2011-01, Vol.98 (1), p.73-78</ispartof><rights>Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4554-d4688262be462a242f979eba55b89507dfd890dd774cdc0d7db10fe7a3ea5403</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23625017$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21136563$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, H.</creatorcontrib><creatorcontrib>Bae, J. M.</creatorcontrib><creatorcontrib>Choi, M. G.</creatorcontrib><creatorcontrib>Noh, J. H.</creatorcontrib><creatorcontrib>Sohn, T. S.</creatorcontrib><creatorcontrib>Kim, S.</creatorcontrib><title>Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
Endoscopic resection of early gastric cancer is a relatively new and attractive treatment, but occasionally fails to remove all cancer lesions completely. This study aimed to elucidate clinicopathological factors that could be helpful in predicting residual tumour in the surgical specimen after incomplete endoscopic submucosal dissection (ESD).
Methods:
Patients who underwent gastrectomy because of incomplete ESD between August 2004 and August 2008 were analysed. Clinicopathological characteristics were reviewed retrospectively from prospectively collected medical records. Patients were classified into groups with and without residual tumour. Pathology results following gastrectomy were compared with those of incomplete ESD.
Results:
A total of 118 patients were included. The incidence of residual tumour in the surgical specimen was 24·6 per cent after incomplete ESD. Elevated/flat‐type cancers, large tumours (at least 2 cm) and those limited to the mucosa had significantly higher incomplete ESD rates. Cancer limited to the mucosa and the presence of tumour in the lateral margin were associated with residual tumour in the surgical specimen (both P = 0·001).
Conclusion:
Radical gastrectomy should be performed if pathological examination reveals a positive lateral resection margin after ESD. Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Incomplete endoscopic resection necessitates surgery</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Dissection - methods</subject><subject>Endoscopy, Gastrointestinal - methods</subject><subject>Female</subject><subject>Gastric Mucosa - surgery</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroscopy - methods</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm, Residual</subject><subject>Prospective Studies</subject><subject>Stomach Neoplasms - pathology</subject><subject>Stomach Neoplasms - surgery</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNpF0UtLxDAQB_Agiq4P8BNIL-KpmkeTtEffjxUVdkHwEtJkKtFusyYtut_eLK56Gob5MTDzR2if4GOCMT2p3-KxpLJYQyPCBM8pEeU6GmGMZU4YZVtoO8Y3jAnDnG6iLUqWTLARmk6G8OqMbjM_9MbPINNNDyFzXWrmLfSQQWd9NH7uTBaHejYYHxO3LkYwvfNd5pvsVcc-JGB0ZyDsoo1GtxH2VnUHTa8up-c3-f3j9e356X1uCs6L3BaiLKmgNRSCalrQppIV1Jrzuqw4lraxZYWtlbIw1mArbU1wA1Iz0LzAbAcd_aydB_8xQOzVzEUDbas78ENUJRGclhUjSR6sZDoArJoHN9NhoX7_kMDhCuiYntGEdIeL_44JyjGRyeU_7tO1sPibE6yWOaiUg1rmoM7uJsv6713s4evP6_CuhGSSq-eHazV-qsYvE3KhLtg3FiOJmA</recordid><startdate>201101</startdate><enddate>201101</enddate><creator>Jung, H.</creator><creator>Bae, J. M.</creator><creator>Choi, M. G.</creator><creator>Noh, J. H.</creator><creator>Sohn, T. S.</creator><creator>Kim, S.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201101</creationdate><title>Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer</title><author>Jung, H. ; Bae, J. M. ; Choi, M. G. ; Noh, J. H. ; Sohn, T. S. ; Kim, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4554-d4688262be462a242f979eba55b89507dfd890dd774cdc0d7db10fe7a3ea5403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Dissection - methods</topic><topic>Endoscopy, Gastrointestinal - methods</topic><topic>Female</topic><topic>Gastric Mucosa - surgery</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroscopy - methods</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm, Residual</topic><topic>Prospective Studies</topic><topic>Stomach Neoplasms - pathology</topic><topic>Stomach Neoplasms - surgery</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jung, H.</creatorcontrib><creatorcontrib>Bae, J. M.</creatorcontrib><creatorcontrib>Choi, M. G.</creatorcontrib><creatorcontrib>Noh, J. H.</creatorcontrib><creatorcontrib>Sohn, T. S.</creatorcontrib><creatorcontrib>Kim, S.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jung, H.</au><au>Bae, J. M.</au><au>Choi, M. G.</au><au>Noh, J. H.</au><au>Sohn, T. S.</au><au>Kim, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2011-01</date><risdate>2011</risdate><volume>98</volume><issue>1</issue><spage>73</spage><epage>78</epage><pages>73-78</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
Endoscopic resection of early gastric cancer is a relatively new and attractive treatment, but occasionally fails to remove all cancer lesions completely. This study aimed to elucidate clinicopathological factors that could be helpful in predicting residual tumour in the surgical specimen after incomplete endoscopic submucosal dissection (ESD).
Methods:
Patients who underwent gastrectomy because of incomplete ESD between August 2004 and August 2008 were analysed. Clinicopathological characteristics were reviewed retrospectively from prospectively collected medical records. Patients were classified into groups with and without residual tumour. Pathology results following gastrectomy were compared with those of incomplete ESD.
Results:
A total of 118 patients were included. The incidence of residual tumour in the surgical specimen was 24·6 per cent after incomplete ESD. Elevated/flat‐type cancers, large tumours (at least 2 cm) and those limited to the mucosa had significantly higher incomplete ESD rates. Cancer limited to the mucosa and the presence of tumour in the lateral margin were associated with residual tumour in the surgical specimen (both P = 0·001).
Conclusion:
Radical gastrectomy should be performed if pathological examination reveals a positive lateral resection margin after ESD. Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Incomplete endoscopic resection necessitates surgery</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>21136563</pmid><doi>10.1002/bjs.7274</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1323 |
| ispartof | British journal of surgery, 2011-01, Vol.98 (1), p.73-78 |
| issn | 0007-1323 1365-2168 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_816528931 |
| source | Oxford Journals Online |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Dissection - methods Endoscopy, Gastrointestinal - methods Female Gastric Mucosa - surgery Gastroenterology. Liver. Pancreas. Abdomen Gastroscopy - methods General aspects Humans Male Medical sciences Middle Aged Neoplasm Invasiveness Neoplasm, Residual Prospective Studies Stomach Neoplasms - pathology Stomach Neoplasms - surgery Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Treatment Outcome Tumors |
| title | Surgical outcome after incomplete endoscopic submucosal dissection of gastric cancer |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T03%3A32%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Surgical%20outcome%20after%20incomplete%20endoscopic%20submucosal%20dissection%20of%20gastric%20cancer&rft.jtitle=British%20journal%20of%20surgery&rft.au=Jung,%20H.&rft.date=2011-01&rft.volume=98&rft.issue=1&rft.spage=73&rft.epage=78&rft.pages=73-78&rft.issn=0007-1323&rft.eissn=1365-2168&rft.coden=BJSUAM&rft_id=info:doi/10.1002/bjs.7274&rft_dat=%3Cproquest_pubme%3E816528931%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4554-d4688262be462a242f979eba55b89507dfd890dd774cdc0d7db10fe7a3ea5403%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=816528931&rft_id=info:pmid/21136563&rfr_iscdi=true |