Continuous antibiotic therapy in chronic granulomatous disease: preliminary communication

A series of nine patients with chronic granulomatous disease have been maintained on continuous nafcillin therapy for a period adequate to allow preliminary evaluation. Clinically significant hepatic sepsis has not occurred since initiation of this program. The effect on extra-hepatic sepsis is not...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1972-12, Vol.50 (6), p.923-925
Main Authors: Philippart, A I, Colodny, A H, Baehner, R L
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-Bacterial Agents - therapeutic use
Child
Chronic Disease
Drainage
Granuloma - drug therapy
Hepatomegaly - drug therapy
Humans
Infection - drug therapy
Lymphadenitis - drug therapy
Nafcillin - administration & dosage
Nafcillin - therapeutic use
Osteomyelitis - drug therapy
Splenomegaly - drug therapy
Sulfisoxazole - therapeutic use
Suppuration - drug therapy
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Description
Summary:A series of nine patients with chronic granulomatous disease have been maintained on continuous nafcillin therapy for a period adequate to allow preliminary evaluation. Clinically significant hepatic sepsis has not occurred since initiation of this program. The effect on extra-hepatic sepsis is not yet clearly established.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.50.6.923