Pathologic Features of Herpesvirus ateles Lymphoma in Cotton-Topped Marmosets (Saguinus oedipus)

Herpesvirus ateles, a latent virus carried by spider monkeys, was inoculated into 12 cotton-topped marmosets. All of these marmosets died of malignant lymphoma, lymphoblastic type. Leukemia developed in 11 of these animals. Of 4 contact control marmosets, 1 also developed malignant lymphoma and leuk...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1972-12, Vol.49 (6), p.1631-1639
Main Authors: Hunt, R. D., Meléndez, L. V., García, F. G., Trum, B. F.
Format: Article
Language:English
Subjects:
Animals
Haplorhini
Herpesviridae - pathogenicity
Leukemia, Lymphoid - blood
Leukemia, Lymphoid - pathology
Leukocyte Count
Liver - pathology
Lymph Nodes - pathology
Lymphoma - blood
Lymphoma - etiology
Lymphoma - pathology
Neoplasms, Experimental - blood
Neoplasms, Experimental - etiology
Neoplasms, Experimental - pathology
Spleen - pathology
Splenomegaly
Thymus Gland - pathology
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Summary:Herpesvirus ateles, a latent virus carried by spider monkeys, was inoculated into 12 cotton-topped marmosets. All of these marmosets died of malignant lymphoma, lymphoblastic type. Leukemia developed in 11 of these animals. Of 4 contact control marmosets, 1 also developed malignant lymphoma and leukemia, which indicated horizontal transmission.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/49.6.1631