Variation on the USP–NF Rotating-Basket Dissolution Apparatus and a New Device for Dissolution Rate Studies of Solid Dosage Forms

Tablet dissolution studies were conducted comparing three devices: the USP‐NF rotating basket, a modification of this called the bent basket, and a newly designed L‐shaped Teflon holder/stirrer. In these studies, the latter two devices were superior to the official device.

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Bibliographic Details
Published in:Journal of pharmaceutical sciences 1973-01, Vol.62 (1), p.130-132
Main Authors: Haringer, Gisela, Poulsen, Boyd J., Havemeyer, Ruth N.
Format: Article
Language:English
Subjects:
Chemistry, Pharmaceutical - instrumentation
Dissolution equipment-modified compendial rotating basket
Dissolution equipment—modified compendial rotating basket, new rotating assembly
Formularies as Topic
Kinetics
new rotating assembly
Pharmacopoeias as Topic
Polytetrafluoroethylene
Solubility
Spectrophotometry
Tablet dissolution-modified compendial rotating basket
Tablet dissolution—modified compendial rotating basket, new rotating assembly
Tablets - analysis
United States
Water
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Description
Summary:Tablet dissolution studies were conducted comparing three devices: the USP‐NF rotating basket, a modification of this called the bent basket, and a newly designed L‐shaped Teflon holder/stirrer. In these studies, the latter two devices were superior to the official device.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600620126