Time-dependent effects of exposure to static magnetic field on glucose and lipid metabolism in rat

• Published in: General physiology and biophysics 2010-12, Vol.29 (4), p.390-395
• Main Authors: Lahbib, Aida, Elferchichi, Myriam, Ghodbane, Soumaya, Belguith, Hatem, Chater, Sihem, Sakly, Mohsen, Abdelmelek, Hafedh
• Format: Article
• Language: English
• Subjects: Animals; Blood Glucose - metabolism; Body Weight; Glucose - metabolism; Kidney - anatomy & histology; Lipid Metabolism; Liver - anatomy & histology; Magnetics; Male; Organ Size; Rats; Rats, Wistar; Time Factors
• ISSN: 0231-5882
• DOI: 10.4149/gpb_2010_04_390

In the following study, we investigate the effects of static magnetic field (SMF) (128 mT, 1 h/day during 5 or 15 consecutive days) on anthropometric parameters, glucose and lipid metabolism in rats. Exposure to SMF during 5 days induced a decrease (-8%, p < 0.05) in relative liver weight and serum insulin concentration (-56%, p < 0.001), while blood glucose level was increased (+10%, p < 0.001). By contrast, the same treatment failed to alter body weight, relative kidney weight and levels of lactate, cholesterol, triglycerides and phospholipids. Exposure to SMF during 15 days induced a decrease (-15 %, p < 0.001) in body weight, liver weight (-15 %, p < 0.05), insulin concentration (-63%, p < 0.001), plasmatic lactate level (-55%, p < 0.05) and increased glucose (+24%, p < 0.001), cholesterol (+30%, p < 0.01,) and phospholipids levels (+58%, p < 0.001), whereas, triglycerides decreased (-28%, p < 0.001). These results showed that SMF effects on glucose and lipid metabolism are time-dependent.