F-18 FDG PET Images for Subcutaneous Panniculitis-like T-Cell Lymphoma

A 14-year-old girl, who had been suffering from intermittent fevers for 2 months, developed painful erythematous plaques on the lower extremities. Laboratory data revealed elevated C-reactive protein, lactate dehydrogenase, and aspartate aminotransferase/alanine aminotransferase (AST/ALT). Blood and...

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Bibliographic Details
Published in:Clinical nuclear medicine 2011-01, Vol.36 (1), p.66-69
Main Authors: Wang, Shan-Ying, Wu, Yen-Wen, Hsiao, Cheng-Hsiang, Li, Meng-Fang, Hsu, Pei-Ying, Yen, Ruoh-Fang
Format: Article
Language:English
Subjects:
Adolescent
Female
Fluorodeoxyglucose F18
Humans
Lymphoma, T-Cell - diagnostic imaging
Lymphoma, T-Cell - pathology
Panniculitis - diagnostic imaging
Panniculitis - pathology
Positron-Emission Tomography
Skin - pathology
Subcutaneous Tissue - diagnostic imaging
Subcutaneous Tissue - pathology
Whole Body Imaging
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Summary:A 14-year-old girl, who had been suffering from intermittent fevers for 2 months, developed painful erythematous plaques on the lower extremities. Laboratory data revealed elevated C-reactive protein, lactate dehydrogenase, and aspartate aminotransferase/alanine aminotransferase (AST/ALT). Blood and urine cultures were negative. CT showed hepatosplenomegaly. F-18 FDG PET revealed multiple patchy uptakes on the subcutaneous surfaces residing mainly at the lower trunk and extremities. The PET images and clinical manifestations appeared indistinguishable from those due to panniculitis while the pathology from skin biopsy demonstrated panniculitis-like T-cell lymphoma. She received chemotherapy and the follow-up PET showed significant resolution of previous abnormal uptakes from the subcutaneous lesions.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e3181f49ac7