Androgen Inhibition of Atherogenesis in Pullets

Continuous testosterone propionate administration, but not pretreatment, inhibited cholesterol-induced coronary atherogenesis in pullets. This inhibition was associated with depression of the plasma total cholesterol, phospholipids. c/p ratio and turbidity. Aortic atherogenesis was not affected.

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Bibliographic Details
Published in:Circulation research 1957-01, Vol.5 (1), p.54-57
Main Authors: Cook, D L, Edgren, R A, Harris, T W
Format: Article
Language:English
Subjects:
Animals
Arteriosclerosis
Atherosclerosis
Chickens
Cholesterol - pharmacology
Female
Humans
Old Medline
Testosterone - pharmacology
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Description
Summary:Continuous testosterone propionate administration, but not pretreatment, inhibited cholesterol-induced coronary atherogenesis in pullets. This inhibition was associated with depression of the plasma total cholesterol, phospholipids. c/p ratio and turbidity. Aortic atherogenesis was not affected.
ISSN:0009-7330
1524-4571
DOI:10.1161/01.RES.5.1.54