Primary Mammary Tumors Connected to the Host by a Single Artery and Vein

Primary tumors originating in the intermediate inguinal mammary glands of female Buffalo rats were surgically “isolated” from the surrounding tissues, so that one artery and one vein were the only connection between host and tumor. The vein of this tumor was cannulated in situ and tumor blood was co...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1973-05, Vol.50 (5), p.1381-1383
Main Authors: Grantham, Flora H., Hill, Donald M., Gullino, Pietro M.
Format: Article
Language:English
Subjects:
Animals
Arteries - physiopathology
Blood Circulation
Female
Mammary Neoplasms, Experimental - pathology
Mammary Neoplasms, Experimental - physiopathology
Rats
Veins - physiopathology
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Summary:Primary tumors originating in the intermediate inguinal mammary glands of female Buffalo rats were surgically “isolated” from the surrounding tissues, so that one artery and one vein were the only connection between host and tumor. The vein of this tumor was cannulated in situ and tumor blood was collected for several hours. The primary tumor was also removed from the host and perfused as an isolated, intact organ.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/50.5.1381