Lymphosarcomas in Two Gibbons (Hylobates lar) With Associated C-Type Virus

We examined the tissues from 2 cases of lymphosarcoma in gibbons by light and electron microscopy. The animals were part of a group of 6 gibbons purchased together and used in a study on the aging of the spinal column. The animals, a male and a female, were about 3.5 years old at death. Numerous C-t...

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Published in:JNCI : Journal of the National Cancer Institute 1973-07, Vol.51 (1), p.89-94
Main Authors: Snyder, S. P., Dungworth, D. L., Kawakami, T. G., Callaway, E., Lau, D. T-L.
Format: Article
Language:English
Subjects:
Animals
Bone Marrow - pathology
Cells, Cultured
Female
Histiocytes
Hominidae
Liver - pathology
Lymphoid Tissue - cytology
Lymphoma, Non-Hodgkin - microbiology
Lymphoma, Non-Hodgkin - pathology
Lymphoma, Non-Hodgkin - veterinary
Male
Megakaryocytes
Microscopy, Electron
Oncogenic Viruses
Retrospective Studies
Retroviridae
RNA Viruses
Spleen - pathology
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container_issue 1
container_start_page 89
container_title JNCI : Journal of the National Cancer Institute
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creator Snyder, S. P.
Dungworth, D. L.
Kawakami, T. G.
Callaway, E.
Lau, D. T-L.
description We examined the tissues from 2 cases of lymphosarcoma in gibbons by light and electron microscopy. The animals were part of a group of 6 gibbons purchased together and used in a study on the aging of the spinal column. The animals, a male and a female, were about 3.5 years old at death. Numerous C-type virus particles, similar in morphology and apparent mode of production to those of the avian, murine, and feline leukemia-sarcoma complex, were found in all tissues examined. The particles were approximately 100 nm in diameter, with nucleoids of about 65 nm, and were found budding from, and free between, neoplastic lymphoid cells, histiocytic cells, and megakaryocytes.
doi_str_mv 10.1093/jnci/51.1.89
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source Oxford University Press Archive
subjects Animals
Bone Marrow - pathology
Cells, Cultured
Female
Histiocytes
Hominidae
Liver - pathology
Lymphoid Tissue - cytology
Lymphoma, Non-Hodgkin - microbiology
Lymphoma, Non-Hodgkin - pathology
Lymphoma, Non-Hodgkin - veterinary
Male
Megakaryocytes
Microscopy, Electron
Oncogenic Viruses
Retrospective Studies
Retroviridae
RNA Viruses
Spleen - pathology
title Lymphosarcomas in Two Gibbons (Hylobates lar) With Associated C-Type Virus
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