Hemodynamic Effects of Quantitatively Varied Experimental Mitral Regurgitation

Mitral regurgitation was produced in the open-chest dog by permitting blood to flow from left ventricle through a flow meter into the left atrium during systole. The hemodynamic effects of known amounts of regurgitation were studied. Two liters per minute of mitral regurgitant flow had relatively li...

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Bibliographic Details
Published in:Circulation research 1957-09, Vol.5 (5), p.539-545
Main Authors: Braunwald, Eugene, Welch, George H, Sarnoff, Stanley J
Format: Article
Language:English
Subjects:
Chronic Disease
Disease
Heart Diseases
Heart Valve Diseases
Hemodynamics
Humans
Mitral Valve
Mitral Valve Insufficiency
Myocarditis
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Summary:Mitral regurgitation was produced in the open-chest dog by permitting blood to flow from left ventricle through a flow meter into the left atrium during systole. The hemodynamic effects of known amounts of regurgitation were studied. Two liters per minute of mitral regurgitant flow had relatively little effect on effective cardiac output, aortic pressure, left atrial pressure and on the left ventricular function curve.
ISSN:0009-7330
1524-4571
DOI:10.1161/01.RES.5.5.539