Diphoterine for alkali chemical splashes to the skin at alumina refineries

Background  Diphoterine is a commercially available amphoteric, hypertonic, chelating solution used to decontaminate and irrigate chemical splashes. The aim of this study was to evaluate the implementation of Diphoterine at three alumina refineries. This is the largest case series reported to date....

Full description

Saved in:
Bibliographic Details
Published in:International Journal of Dermatology 2010-08, Vol.49 (8), p.894-900
Main Author: Donoghue, A. Michael
Format: Article
Language:English
Subjects:
Accidents, Occupational
Alkalies - adverse effects
Aluminum Oxide
Biological and medical sciences
Buffers
Burns, Chemical - drug therapy
Burns, Chemical - nursing
Decontamination - methods
Dermatology
Humans
Medical sciences
Occupational Health Nursing - methods
Occupational Health Services - methods
Organic Chemicals - therapeutic use
Skin - drug effects
Skin - injuries
Treatment Outcome
Water
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background  Diphoterine is a commercially available amphoteric, hypertonic, chelating solution used to decontaminate and irrigate chemical splashes. The aim of this study was to evaluate the implementation of Diphoterine at three alumina refineries. This is the largest case series reported to date. Methods  One hundred eighty cases of alkali splashes to the skin were evaluated clinically. Two groups were compared; those who had applied Diphoterine first and those who had applied water first. Results  There were no signs of chemical burn in 52.9% of the group who applied Diphoterine first compared with 21.4% of the group who applied water first. Only 7.9% of the group who applied Diphoterine first had blisters or more severe signs compared with 23.8% of the group who applied water first. The differences were statistically significant (P 
ISSN:0011-9059
1365-4632
DOI:10.1111/j.1365-4632.2009.04397.x