Progression of Segment-Specific Carotid Artery Intima-Media Thickness in Young Adults (from the Bogalusa Heart Study)

Carotid intima-media thickness (CIMT) progression is predictive of future cardiovascular events in middle-age and older adults. However, information is scant on segment-specific CIMT progression by race (black vs white) and gender and its predictors during short-term follow-up in asymptomatic young...

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Bibliographic Details
Published in:The American journal of cardiology 2011, Vol.107 (1), p.114-119
Main Authors: Nguyen, Quoc Manh, MD, MPH, Toprak, Ahmet, MD, Xu, Ji-Hua, MD, Srinivasan, Sathanur R., PhD, Chen, Wei, MD, PhD, Berenson, Gerald S., MD
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Carotid Arteries - diagnostic imaging
Female
Follow-Up Studies
Humans
Male
Medical sciences
Multivariate analysis
Predictive Value of Tests
Risk Assessment
Risk Factors
Tunica Intima - diagnostic imaging
Tunica Media - diagnostic imaging
Ultrasonic imaging
Ultrasonography
Veins & arteries
Young adults
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Summary:Carotid intima-media thickness (CIMT) progression is predictive of future cardiovascular events in middle-age and older adults. However, information is scant on segment-specific CIMT progression by race (black vs white) and gender and its predictors during short-term follow-up in asymptomatic young adults. B-mode ultrasound images of the far walls of both carotid arteries were obtained in 842 subjects aged 24 to 43 years and enrolled in the Bogalusa Heart Study (70% whites and 42% men). The CIMT and cardiometabolic risk variables were measured at baseline and after an average of 2.4 years. The mean CIMT progression rates/year adjusted for age, race, and gender were greatest at the bulb, followed by the internal and common carotid segments (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2010.08.054