Studies on a feminizing ovarian mesenchymoma (granulosa cell tumor). I. Aspiration biopsy cytology, histology, and ultrastructure

A granulosa cell tumor in a 69‐year‐old woman was diagnosed by aspiration biopsy cytology, and different regions were further studied by light and electron microscopy. An almost continuous series of structures, from areas closely imitating normal ovarian follicles and follicular granulosa cells, to...

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Bibliographic Details
Published in:Cancer 1973-12, Vol.32 (6), p.1360-1369
Main Authors: Bjersing, L., Frankendal, B., Ångström, T.
Format: Article
Language:English
Subjects:
Aged
Biopsy, Needle
Estrogens - metabolism
Female
Granulosa Cell Tumor - pathology
Granulosa Cell Tumor - physiopathology
Humans
Microscopy, Electron
Ovarian Neoplasms - pathology
Ovarian Neoplasms - physiopathology
Ovary - pathology
Paraneoplastic Endocrine Syndromes
Citations: Items that this one cites
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Summary:A granulosa cell tumor in a 69‐year‐old woman was diagnosed by aspiration biopsy cytology, and different regions were further studied by light and electron microscopy. An almost continuous series of structures, from areas closely imitating normal ovarian follicles and follicular granulosa cells, to minor regions with theca‐like elements was found. The histogenesis, fine structure, and endocrine activity of steroid producing ovarian tumors was discussed, and it was concluded that feminizing or virilizing ovarian mesenchymoma is a suitable collective term for these tumors.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197312)32:6<1360::AID-CNCR2820320613>3.0.CO;2-S