MATERNAL AND FOETAL CARDIOVASCULAR AND ACID-BASE CHANGES DURING KETAMINE ANAESTHESIA IN PREGNANT EWES

In the pregnant ewe near term, an anaesthetic dose of ketamine (5 mg/kg) increased maternal blood pressure slightly (15% from control) and caused no deleterious effects on the foetal cardiovascular or acid-base status. Uterine blood flow increased concomitant with the rise in maternal arterial press...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1973-11, Vol.45 (11), p.1111-1115
Main Authors: LEVINSON, G, SHNIDER, S.M., GILDEA, J.E., DELORIMIER, A.A.
Format: Article
Language:English
Subjects:
Acid-Base Equilibrium - drug effects
Anesthesia, Spinal
Animals
Blood Flow Velocity
Blood Pressure - drug effects
Carbon Dioxide - blood
Female
Fetus - drug effects
Heart Rate - drug effects
Hydrogen-Ion Concentration
Injections, Intravenous
Ketamine - pharmacology
Pregnancy
Sheep
Stimulation, Chemical
Uterus - blood supply
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Description
Summary:In the pregnant ewe near term, an anaesthetic dose of ketamine (5 mg/kg) increased maternal blood pressure slightly (15% from control) and caused no deleterious effects on the foetal cardiovascular or acid-base status. Uterine blood flow increased concomitant with the rise in maternal arterial pressure.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/45.11.1111