Cardiac Hypertrophy in Rats with Phenylhydrazine Anemia

The effect of phenylhydrazine-produced anemia upon the hearts of rats was studied with observations upon the accompanying hypertrophy. Results indicated that the mechanism of hypertrophy under these conditions may be one of myocardial injury rather than mechanical.

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Bibliographic Details
Published in:Circulation research 1958-11, Vol.6 (6), p.765-770
Main Authors: Norman, Tom D, Mcbroom, Robert D
Format: Article
Language:English
Subjects:
Anemia
Animals
Cardiomegaly
Old Medline
Phenylhydrazines - pharmacology
Rats
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Description
Summary:The effect of phenylhydrazine-produced anemia upon the hearts of rats was studied with observations upon the accompanying hypertrophy. Results indicated that the mechanism of hypertrophy under these conditions may be one of myocardial injury rather than mechanical.
ISSN:0009-7330
1524-4571
DOI:10.1161/01.RES.6.6.765