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Epithelial–mesenchymal transition in the skin
Abstract Epithelial–mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin...
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| Published in: | Journal of dermatological science 2011-01, Vol.61 (1), p.7-13 |
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| Main Authors: | , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c475t-af6c5feca21de7b202e3d2dc600c2dd1ab3e03b5b491544d1bbf74d2cbce78b13 |
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| container_end_page | 13 |
| container_issue | 1 |
| container_start_page | 7 |
| container_title | Journal of dermatological science |
| container_volume | 61 |
| creator | Nakamura, Motonobu Tokura, Yoshiki |
| description | Abstract Epithelial–mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, and malignant cutaneous cancers, including squamous cell carcinoma and melanoma. |
| doi_str_mv | 10.1016/j.jdermsci.2010.11.015 |
| format | article |
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Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, and malignant cutaneous cancers, including squamous cell carcinoma and melanoma.</description><identifier>ISSN: 0923-1811</identifier><identifier>EISSN: 1873-569X</identifier><identifier>DOI: 10.1016/j.jdermsci.2010.11.015</identifier><identifier>PMID: 21167690</identifier><language>eng</language><publisher>Netherlands: Elsevier Ireland Ltd</publisher><subject>Carcinoma, Squamous Cell - etiology ; Carcinoma, Squamous Cell - metabolism ; Dermatology ; Epithelial-Mesenchymal Transition - physiology ; Epithelial–mesenchymal transition ; Fibrosis ; Fibrosis - pathology ; Humans ; Melanoma - etiology ; Melanoma - metabolism ; Signal Transduction ; Skin - growth & development ; Skin - metabolism ; Skin - pathology ; Skin Neoplasms - etiology ; Skin Neoplasms - metabolism ; SNAI1 ; Snail ; Snail Family Transcription Factors ; Systemic sclerosis ; Transcription Factors - chemistry ; Transcription Factors - metabolism ; Wound healing ; Wound Healing - physiology</subject><ispartof>Journal of dermatological science, 2011-01, Vol.61 (1), p.7-13</ispartof><rights>Japanese Society for Investigative Dermatology</rights><rights>2010 Japanese Society for Investigative Dermatology</rights><rights>Copyright © 2010 Japanese Society for Investigative Dermatology. 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| fulltext | fulltext |
| identifier | ISSN: 0923-1811 |
| ispartof | Journal of dermatological science, 2011-01, Vol.61 (1), p.7-13 |
| issn | 0923-1811 1873-569X |
| language | eng |
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| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - metabolism Dermatology Epithelial-Mesenchymal Transition - physiology Epithelial–mesenchymal transition Fibrosis Fibrosis - pathology Humans Melanoma - etiology Melanoma - metabolism Signal Transduction Skin - growth & development Skin - metabolism Skin - pathology Skin Neoplasms - etiology Skin Neoplasms - metabolism SNAI1 Snail Snail Family Transcription Factors Systemic sclerosis Transcription Factors - chemistry Transcription Factors - metabolism Wound healing Wound Healing - physiology |
| title | Epithelial–mesenchymal transition in the skin |
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