Three-dimensional microwell arrays for cell culture

We propose the concept of three-dimensional (3D) microwell arrays for cell culture applications and highlight the importance of oxygen diffusion through pores in all three dimensions to enhance cell viability.

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Bibliographic Details
Published in:Lab on a chip 2011-01, Vol.11 (1), p.127-131
Main Authors: Randall, Christina L, Kalinin, Yevgeniy V, Jamal, Mustapha, Manohar, Tanmay, Gracias, David H
Format: Article
Language:English
Subjects:
Animals
Cell Culture Techniques - instrumentation
Cell Line
Cell Survival
Equipment Design
Insulin - metabolism
Oxygen - metabolism
Tissue Array Analysis - instrumentation
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Description
Summary:We propose the concept of three-dimensional (3D) microwell arrays for cell culture applications and highlight the importance of oxygen diffusion through pores in all three dimensions to enhance cell viability.
ISSN:1473-0197
1473-0189
DOI:10.1039/c0lc00368a