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Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program
Background: Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high‐risk, complex cardiovascular risk state. Methods: An estimated glomerular filtration rate
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| Published in: | Internal medicine journal 2010-12, Vol.40 (12), p.833-841 |
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| creator | McCullough, P. A. Whaley-Connell, A. Brown, W. W. Collins, A. J. Chen, S.-C. Li, S. Norris, K. C. Jurkovitz, C. McFarlane, S. Obialo, C. Sowers, J. Stevens, L. Vassalotti, J. A. Bakris, G. L. |
| description | Background: Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high‐risk, complex cardiovascular risk state.
Methods: An estimated glomerular filtration rate |
| doi_str_mv | 10.1111/j.1445-5994.2009.02158.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_822555619</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>822555619</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4068-cf0951d0fdd4b4bc8ae36686ff170c4a3bd8ca3ee0edcd7cbe1f17430973573f3</originalsourceid><addsrcrecordid>eNqNkEFv1DAQhS0EoqXwF5BvnBLs2I7jAwe0KqVLFziAkLhYjj2h3ibx1k62u_-epCl7Zg6ekea9N_KHEKYkp1O93-aUc5EJpXheEKJyUlBR5Ydn6Py0eP4484wows7Qq5S2hFDJFH-JzgpKlSqK4hztVyY6H_Ym2bE1EUef7nAXnG-8NYMPPfY93pk4eOt3ph8SfvDDLbYhht7EI3Y-gUmAk40APThcH_FwC_iLdz0c8aWJ7fTuTTsuad9j-BNN9xq9aEyb4M1Tv0A_P13-WH3Obr5dXa8-3mSWk7LKbEOUoI40zvGa17YywMqyKpuGSmK5YbWrrGEABJx10tZApw1nREkmJGvYBXq35O5iuB8hDbrzyULbmh7CmHRVFEKIkqpJWS1KG0NKERq9i76bvqgp0TN0vdUzWz2z1TN0_QhdHybr26cjY92BOxn_UZ4EHxbBg2_h-N_B-nqznqfJny1-nwY4nPwm3ulSMin0r69Xev17s95IJTVjfwHziqKm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>822555619</pqid></control><display><type>article</type><title>Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>McCullough, P. A. ; Whaley-Connell, A. ; Brown, W. W. ; Collins, A. J. ; Chen, S.-C. ; Li, S. ; Norris, K. C. ; Jurkovitz, C. ; McFarlane, S. ; Obialo, C. ; Sowers, J. ; Stevens, L. ; Vassalotti, J. A. ; Bakris, G. L.</creator><creatorcontrib>McCullough, P. A. ; Whaley-Connell, A. ; Brown, W. W. ; Collins, A. J. ; Chen, S.-C. ; Li, S. ; Norris, K. C. ; Jurkovitz, C. ; McFarlane, S. ; Obialo, C. ; Sowers, J. ; Stevens, L. ; Vassalotti, J. A. ; Bakris, G. L. ; Kidney Early Evaluation Program (KEEP) Investigators</creatorcontrib><description><![CDATA[Background: Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high‐risk, complex cardiovascular risk state.
Methods: An estimated glomerular filtration rate <60 mL/min/1.73 m2 or a urine albumin : creatinine ratio (ACR) ≥ 30 mg/g (3.4 mg/mmol) defined CKD.
Results: Of 70 454 volunteers screened the mean age was 53.5 ± 15.7 years and 68.3% were female. A total of 5410 (7.7%) had a self‐reported history of CAD; 1295 (1.8%) had a history of prior percutaneous coronary intervention (PCI); and 1124 (1.6%) had a prior history of coronary artery bypass surgery (CABG). Multivariate analysis for the outcome of suboptimal CAD risk management (composite of systolic blood pressure ≥130 mmHg, glucose ≥125 mg/dL (6.9 mmol/L) for diabetics, total cholesterol ≥200 mg/dL (5.2 mmol/L), or current smoking; n= 38 746/53 403, 72.5%) revealed older age (per year) (odds ratio (OR) = 1.04, 95% confidence interval (CI) 1.03–1.04, P < 0.0001), male gender (OR = 1.40, 95% CI 1.34–1.47, P < 0.0001), ACR ≥ 30 mg/g (3.4 mg/mmol) (OR = 1.66, 95% CI 1.55–1.79, P < 0.0001), body mass index (per kg/m2) (OR = 1.06, 95% CI 1.06–1.06, P < 0.0001), CAD without a history of revascularization (OR = 1.14, 95% CI 1.02–1.28, P= 0.02) and care received by a nephrologist (OR = 1.49, 95% CI 1.22–1.83, P < 0.0001) were associated with worse risk factor control. Prior coronary revascularization and being under the care of a cardiologist were not associated with either improved or suboptimal risk factor control.
Conclusions: Chronic kidney disease is associated with overall poor rates of CAD risk factor control.]]></description><identifier>ISSN: 1444-0903</identifier><identifier>EISSN: 1445-5994</identifier><identifier>DOI: 10.1111/j.1445-5994.2009.02158.x</identifier><identifier>PMID: 21199222</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>Adult ; Aged ; bypass surgery ; cardiovascular disease ; Cardiovascular Diseases - diagnosis ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - prevention & control ; chronic kidney disease ; Coronary Disease - diagnosis ; Coronary Disease - etiology ; Coronary Disease - prevention & control ; Early Diagnosis ; Evaluation Studies as Topic ; Female ; Humans ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - diagnosis ; Kidney Function Tests - methods ; Kidney Function Tests - standards ; Male ; Mass Screening - methods ; Mass Screening - standards ; microalbuminuria ; Middle Aged ; percutaneous coronary intervention ; Risk Factors ; Risk Reduction Behavior</subject><ispartof>Internal medicine journal, 2010-12, Vol.40 (12), p.833-841</ispartof><rights>2010 The Authors. Internal Medicine Journal © 2010 Royal Australasian College of Physicians</rights><rights>2010 The Authors. Internal Medicine Journal © 2010 Royal Australasian College of Physicians.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4068-cf0951d0fdd4b4bc8ae36686ff170c4a3bd8ca3ee0edcd7cbe1f17430973573f3</citedby><cites>FETCH-LOGICAL-c4068-cf0951d0fdd4b4bc8ae36686ff170c4a3bd8ca3ee0edcd7cbe1f17430973573f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21199222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McCullough, P. A.</creatorcontrib><creatorcontrib>Whaley-Connell, A.</creatorcontrib><creatorcontrib>Brown, W. W.</creatorcontrib><creatorcontrib>Collins, A. J.</creatorcontrib><creatorcontrib>Chen, S.-C.</creatorcontrib><creatorcontrib>Li, S.</creatorcontrib><creatorcontrib>Norris, K. C.</creatorcontrib><creatorcontrib>Jurkovitz, C.</creatorcontrib><creatorcontrib>McFarlane, S.</creatorcontrib><creatorcontrib>Obialo, C.</creatorcontrib><creatorcontrib>Sowers, J.</creatorcontrib><creatorcontrib>Stevens, L.</creatorcontrib><creatorcontrib>Vassalotti, J. A.</creatorcontrib><creatorcontrib>Bakris, G. L.</creatorcontrib><creatorcontrib>Kidney Early Evaluation Program (KEEP) Investigators</creatorcontrib><title>Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program</title><title>Internal medicine journal</title><addtitle>Intern Med J</addtitle><description><![CDATA[Background: Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high‐risk, complex cardiovascular risk state.
Methods: An estimated glomerular filtration rate <60 mL/min/1.73 m2 or a urine albumin : creatinine ratio (ACR) ≥ 30 mg/g (3.4 mg/mmol) defined CKD.
Results: Of 70 454 volunteers screened the mean age was 53.5 ± 15.7 years and 68.3% were female. A total of 5410 (7.7%) had a self‐reported history of CAD; 1295 (1.8%) had a history of prior percutaneous coronary intervention (PCI); and 1124 (1.6%) had a prior history of coronary artery bypass surgery (CABG). Multivariate analysis for the outcome of suboptimal CAD risk management (composite of systolic blood pressure ≥130 mmHg, glucose ≥125 mg/dL (6.9 mmol/L) for diabetics, total cholesterol ≥200 mg/dL (5.2 mmol/L), or current smoking; n= 38 746/53 403, 72.5%) revealed older age (per year) (odds ratio (OR) = 1.04, 95% confidence interval (CI) 1.03–1.04, P < 0.0001), male gender (OR = 1.40, 95% CI 1.34–1.47, P < 0.0001), ACR ≥ 30 mg/g (3.4 mg/mmol) (OR = 1.66, 95% CI 1.55–1.79, P < 0.0001), body mass index (per kg/m2) (OR = 1.06, 95% CI 1.06–1.06, P < 0.0001), CAD without a history of revascularization (OR = 1.14, 95% CI 1.02–1.28, P= 0.02) and care received by a nephrologist (OR = 1.49, 95% CI 1.22–1.83, P < 0.0001) were associated with worse risk factor control. Prior coronary revascularization and being under the care of a cardiologist were not associated with either improved or suboptimal risk factor control.
Conclusions: Chronic kidney disease is associated with overall poor rates of CAD risk factor control.]]></description><subject>Adult</subject><subject>Aged</subject><subject>bypass surgery</subject><subject>cardiovascular disease</subject><subject>Cardiovascular Diseases - diagnosis</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>chronic kidney disease</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - etiology</subject><subject>Coronary Disease - prevention & control</subject><subject>Early Diagnosis</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - diagnosis</subject><subject>Kidney Function Tests - methods</subject><subject>Kidney Function Tests - standards</subject><subject>Male</subject><subject>Mass Screening - methods</subject><subject>Mass Screening - standards</subject><subject>microalbuminuria</subject><subject>Middle Aged</subject><subject>percutaneous coronary intervention</subject><subject>Risk Factors</subject><subject>Risk Reduction Behavior</subject><issn>1444-0903</issn><issn>1445-5994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqNkEFv1DAQhS0EoqXwF5BvnBLs2I7jAwe0KqVLFziAkLhYjj2h3ibx1k62u_-epCl7Zg6ekea9N_KHEKYkp1O93-aUc5EJpXheEKJyUlBR5Ydn6Py0eP4484wows7Qq5S2hFDJFH-JzgpKlSqK4hztVyY6H_Ym2bE1EUef7nAXnG-8NYMPPfY93pk4eOt3ph8SfvDDLbYhht7EI3Y-gUmAk40APThcH_FwC_iLdz0c8aWJ7fTuTTsuad9j-BNN9xq9aEyb4M1Tv0A_P13-WH3Obr5dXa8-3mSWk7LKbEOUoI40zvGa17YywMqyKpuGSmK5YbWrrGEABJx10tZApw1nREkmJGvYBXq35O5iuB8hDbrzyULbmh7CmHRVFEKIkqpJWS1KG0NKERq9i76bvqgp0TN0vdUzWz2z1TN0_QhdHybr26cjY92BOxn_UZ4EHxbBg2_h-N_B-nqznqfJny1-nwY4nPwm3ulSMin0r69Xev17s95IJTVjfwHziqKm</recordid><startdate>201012</startdate><enddate>201012</enddate><creator>McCullough, P. A.</creator><creator>Whaley-Connell, A.</creator><creator>Brown, W. W.</creator><creator>Collins, A. J.</creator><creator>Chen, S.-C.</creator><creator>Li, S.</creator><creator>Norris, K. C.</creator><creator>Jurkovitz, C.</creator><creator>McFarlane, S.</creator><creator>Obialo, C.</creator><creator>Sowers, J.</creator><creator>Stevens, L.</creator><creator>Vassalotti, J. A.</creator><creator>Bakris, G. L.</creator><general>Blackwell Publishing Asia</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201012</creationdate><title>Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program</title><author>McCullough, P. A. ; Whaley-Connell, A. ; Brown, W. W. ; Collins, A. J. ; Chen, S.-C. ; Li, S. ; Norris, K. C. ; Jurkovitz, C. ; McFarlane, S. ; Obialo, C. ; Sowers, J. ; Stevens, L. ; Vassalotti, J. A. ; Bakris, G. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4068-cf0951d0fdd4b4bc8ae36686ff170c4a3bd8ca3ee0edcd7cbe1f17430973573f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>bypass surgery</topic><topic>cardiovascular disease</topic><topic>Cardiovascular Diseases - diagnosis</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>chronic kidney disease</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - etiology</topic><topic>Coronary Disease - prevention & control</topic><topic>Early Diagnosis</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - diagnosis</topic><topic>Kidney Function Tests - methods</topic><topic>Kidney Function Tests - standards</topic><topic>Male</topic><topic>Mass Screening - methods</topic><topic>Mass Screening - standards</topic><topic>microalbuminuria</topic><topic>Middle Aged</topic><topic>percutaneous coronary intervention</topic><topic>Risk Factors</topic><topic>Risk Reduction Behavior</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McCullough, P. A.</creatorcontrib><creatorcontrib>Whaley-Connell, A.</creatorcontrib><creatorcontrib>Brown, W. W.</creatorcontrib><creatorcontrib>Collins, A. J.</creatorcontrib><creatorcontrib>Chen, S.-C.</creatorcontrib><creatorcontrib>Li, S.</creatorcontrib><creatorcontrib>Norris, K. C.</creatorcontrib><creatorcontrib>Jurkovitz, C.</creatorcontrib><creatorcontrib>McFarlane, S.</creatorcontrib><creatorcontrib>Obialo, C.</creatorcontrib><creatorcontrib>Sowers, J.</creatorcontrib><creatorcontrib>Stevens, L.</creatorcontrib><creatorcontrib>Vassalotti, J. A.</creatorcontrib><creatorcontrib>Bakris, G. L.</creatorcontrib><creatorcontrib>Kidney Early Evaluation Program (KEEP) Investigators</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal medicine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McCullough, P. A.</au><au>Whaley-Connell, A.</au><au>Brown, W. W.</au><au>Collins, A. J.</au><au>Chen, S.-C.</au><au>Li, S.</au><au>Norris, K. C.</au><au>Jurkovitz, C.</au><au>McFarlane, S.</au><au>Obialo, C.</au><au>Sowers, J.</au><au>Stevens, L.</au><au>Vassalotti, J. A.</au><au>Bakris, G. L.</au><aucorp>Kidney Early Evaluation Program (KEEP) Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program</atitle><jtitle>Internal medicine journal</jtitle><addtitle>Intern Med J</addtitle><date>2010-12</date><risdate>2010</risdate><volume>40</volume><issue>12</issue><spage>833</spage><epage>841</epage><pages>833-841</pages><issn>1444-0903</issn><eissn>1445-5994</eissn><abstract><![CDATA[Background: Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high‐risk, complex cardiovascular risk state.
Methods: An estimated glomerular filtration rate <60 mL/min/1.73 m2 or a urine albumin : creatinine ratio (ACR) ≥ 30 mg/g (3.4 mg/mmol) defined CKD.
Results: Of 70 454 volunteers screened the mean age was 53.5 ± 15.7 years and 68.3% were female. A total of 5410 (7.7%) had a self‐reported history of CAD; 1295 (1.8%) had a history of prior percutaneous coronary intervention (PCI); and 1124 (1.6%) had a prior history of coronary artery bypass surgery (CABG). Multivariate analysis for the outcome of suboptimal CAD risk management (composite of systolic blood pressure ≥130 mmHg, glucose ≥125 mg/dL (6.9 mmol/L) for diabetics, total cholesterol ≥200 mg/dL (5.2 mmol/L), or current smoking; n= 38 746/53 403, 72.5%) revealed older age (per year) (odds ratio (OR) = 1.04, 95% confidence interval (CI) 1.03–1.04, P < 0.0001), male gender (OR = 1.40, 95% CI 1.34–1.47, P < 0.0001), ACR ≥ 30 mg/g (3.4 mg/mmol) (OR = 1.66, 95% CI 1.55–1.79, P < 0.0001), body mass index (per kg/m2) (OR = 1.06, 95% CI 1.06–1.06, P < 0.0001), CAD without a history of revascularization (OR = 1.14, 95% CI 1.02–1.28, P= 0.02) and care received by a nephrologist (OR = 1.49, 95% CI 1.22–1.83, P < 0.0001) were associated with worse risk factor control. Prior coronary revascularization and being under the care of a cardiologist were not associated with either improved or suboptimal risk factor control.
Conclusions: Chronic kidney disease is associated with overall poor rates of CAD risk factor control.]]></abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>21199222</pmid><doi>10.1111/j.1445-5994.2009.02158.x</doi><tpages>9</tpages></addata></record> |
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| subjects | Adult Aged bypass surgery cardiovascular disease Cardiovascular Diseases - diagnosis Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control chronic kidney disease Coronary Disease - diagnosis Coronary Disease - etiology Coronary Disease - prevention & control Early Diagnosis Evaluation Studies as Topic Female Humans Kidney Failure, Chronic - complications Kidney Failure, Chronic - diagnosis Kidney Function Tests - methods Kidney Function Tests - standards Male Mass Screening - methods Mass Screening - standards microalbuminuria Middle Aged percutaneous coronary intervention Risk Factors Risk Reduction Behavior |
| title | Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program |
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