Studies on adrenal cortical activity in patients with rheumatoid arthritis: The diurnal pattern and twenty‐four hour levels of urinary total 17‐hydroxycorticosteroids and 17‐ketosteroids

The total and diurnal patterns of excretion of 17‐hydroxycorticosteroids and 17‐ketosteroids were studied in both ambulatory and hospitalized rheumatoid patients and in comparable controls. While daily excretion of 17‐ketosteroids was within normal limits, the excretion of 17‐hydroxycorticosteroids...

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Bibliographic Details
Published in:Arthritis and rheumatism 1959-04, Vol.2 (2), p.114-126
Main Authors: Hill, S. Richardson, Holley, Howard L., Ulloa, Alexander, Starnes, Willard R., Hibbitt, Lester L., McNeil, Jean H.
Format: Article
Language:English
Subjects:
17-Hydroxycorticosteroids
17-Ketosteroids
Adrenal Cortex Hormones - urine
Arthritis
Arthritis, Rheumatoid - urine
Hormones - urine
Humans
Old Medline
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Summary:The total and diurnal patterns of excretion of 17‐hydroxycorticosteroids and 17‐ketosteroids were studied in both ambulatory and hospitalized rheumatoid patients and in comparable controls. While daily excretion of 17‐ketosteroids was within normal limits, the excretion of 17‐hydroxycorticosteroids was diminished, due to a lower output during the early morning hours. Le totales e le curvas diurne del excretion de 17‐hydroxycorticosteroids e 17‐cetosteroides esseva studiate in patientes rheumatoide‐ambulatori e hospitalisate‐e in comparabile subjectos de controlo. Durante que le excretion diurne de 17‐cetosteroides se teneva intra le limites normal, le excretion de 17‐hydroxycorticosteroides esseva reducite in consequentia de un plus basse rendimento durante le prime horas matinal.
ISSN:0004-3591
1529-0131
DOI:10.1002/1529-0131(195904)2:2<114::AID-ART1780020204>3.0.CO;2-V