Effect of Protein-free Diet on the Vitamin A Storage in the Rat Liver

SEVERAL workers 1–4 have reported that diets low in protein reduced the storage of vitamin A in the liver and increased the rate at which stored vitamin A was depleted. On the basis of such data, a conclusion was drawn by investigators that protein is a necessary dietary constituent for normal stora...

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Bibliographic Details
Published in:Nature (London) 1959-06, Vol.183 (4675), p.1597-1597
Main Authors: RECHCIGL, M, BERGER, S, LOOSLI, J. K, WILLIAMS, H. H
Format: Article
Language:English
Subjects:
Animals
Biochemical Phenomena
Diet, Protein-Restricted
Humanities and Social Sciences
letter
Lipid Metabolism
Liver - metabolism
multidisciplinary
Old Medline
Protein Deficiency
Rats
Science
Science (multidisciplinary)
Vitamin A - metabolism
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Summary:SEVERAL workers 1–4 have reported that diets low in protein reduced the storage of vitamin A in the liver and increased the rate at which stored vitamin A was depleted. On the basis of such data, a conclusion was drawn by investigators that protein is a necessary dietary constituent for normal storage and utilization of vitamin A. The work described here was designed to test the validity of the former hypothesis by comparing hepatic vitamin A storage in young rats fed an 18 per cent casein diet and in animals fed a protein-free diet under the conditions of controlled intake of vitamin A.
ISSN:0028-0836
1476-4687
DOI:10.1038/1831597a0