The variable spectrum of echocardiographic manifestations of the mitral valve prolapse syndrome

• Published in: Circulation (New York, N.Y.) N.Y.), 1974-07, Vol.50 (1), p.33-41
• Main Authors: DeMaria, A N, King, J F, Bogren, H G, Lies, J E, Mason, D T
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Chordae Tendineae - injuries; Cineangiography; Dilatation; Echocardiography; Female; Heart Auscultation; Heart Valve Diseases - diagnostic imaging; Heart Ventricles - diagnostic imaging; Humans; Male; Marfan Syndrome - complications; Middle Aged; Mitral Valve - physiopathology; Mitral Valve Insufficiency - diagnosis; Mitral Valve Insufficiency - physiopathology; Phonocardiography; Pulmonary Artery; Rupture - diagnosis; Syndrome; Ultrasonography; Vascular Diseases - diagnosis
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/01.CIR.50.1.33

The variety of echographic features associated with the mitral valve prolapse syndrome (MVPS) is not yet completely understood. Therefore, ultrasound recordings were obtained in 33 patients in whom mitral prolapse had been documented by biplane left ventricular cineangiography. Echographic abnormailities of the mitral leaflets during systole were recorded in 26/27 MVPS patients and 6/6 with ruptured chordae tendineae. In MVPS, the midsystolic mitral buckling, emphasized in early echocardiographic studies, was observed in only 12 patients. In our study, the most common aberrancy was abnormal pansystolic mitral motion in 14 patients, which in 12 was similar to the pansystolic bowing observed in all six patients with torn chordae. An additional echographic abnormality in MVPS was localized mitral collapse throughout systole in 10/14 patients with pansystolic prolapse; this finding was the most striking defect noted in five, in two of whom it was the only disturbance. Phonocardiography in MVPS showed typical midsystolic click and/or late systolic murmur in only 15/26 patients of whom ten had midsystolic mitral buckling. A variety of systolic clicks and/or murmurs occurred in the 14 patients with generalized bowing and/or localized collapse throughout systole on echocardiography. Thus, the mitral echographic spectrum of MVPS is comprised of three different abnormal patterns of systolic prolapse: buckling in midsystole, pansystolic bowing, and pansystolic collapse. These echocardiographic disorders commonly occur in the absence of classical auscultatory findings in MVPS and the most frequent abnormality on ultrasound is pansystolic bowing of both mitral leaflets.