Effect of Fragmentation on Interferon Induction by Double-stranded Virus RNA

Department of Biochemistry Imperial College of Science and Technology, London SW7, U.K. Fragmentation by several techniques of the double-stranded RNA of Penicillium chrysogenum viruses reduces its in vivo interferon-inducing capacity in mice. * Present address: Rega Institute for Medical Research,...

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Bibliographic Details
Published in:Journal of general virology 1974-05, Vol.23 (2), p.191-195
Main Authors: Edy, V. G, Szekely, Maria, Himmelweit, F, Chain, E. B
Format: Article
Language:English
Subjects:
Animals
Interferon Inducers
Mice
Penicillium chrysogenum
Plant Viruses
Ribonucleases
RNA Viruses
RNA, Viral
Ultrasonics
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Summary:Department of Biochemistry Imperial College of Science and Technology, London SW7, U.K. Fragmentation by several techniques of the double-stranded RNA of Penicillium chrysogenum viruses reduces its in vivo interferon-inducing capacity in mice. * Present address: Rega Institute for Medical Research, University of Leuven, B-3000 Leuven, Belgium. Received 19 November 1973; accepted 14 January 1974.
ISSN:0022-1317
1465-2099
DOI:10.1099/0022-1317-23-2-191