ISOLATION AND CHARACTERIZATION OF NRCS-15, A NEW IRON-CONTAINING ANTIBIOTIC

A new iron-containing antibiotic named NRCS-15 was isolated from a Streptomyces strain. The antibiotic inhibits the growth of Gram-positive bacteria. The antibiotic is similar to the sideromycin group of antibiotics in that it contains iron but it differs in some other characters. Antibiotic NRCS-15...

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Bibliographic Details
Published in:Journal of antibiotics 1974, Vol.27(1), pp.14-19
Main Author: HAROUN, BAKRY M.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - analysis
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Chromatography
Hydrolysis
Iron - analysis
Peptides - analysis
Peptides - isolation & purification
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Streptomyces - analysis
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Summary:A new iron-containing antibiotic named NRCS-15 was isolated from a Streptomyces strain. The antibiotic inhibits the growth of Gram-positive bacteria. The antibiotic is similar to the sideromycin group of antibiotics in that it contains iron but it differs in some other characters. Antibiotic NRCS-15 liberated 8 amino and 3 organic acids on hydrolysis. The morphological and physiological characteristics of the producing organism as well as the isolation and properties of the antibiotic are described.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.27.14