Studies on Carbohydrate Digestibility and Weight Gain Response in Rats Fed Dietary Sucrose, Glucose or Fructose

A study was made of carbohydrate digestibility and weight gain response in rats fed sucrose, glucose or fructose at varying levels in the diet. In a long-term experiment with older rats, sucrose-fed animals attained a greater mature weight than glucose- and fructose-fed animals. In a digestibility s...

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Bibliographic Details
Published in:Nutrition and metabolism (Basel) 1974-01, Vol.17 (1), p.37-46
Main Authors: MacRae, A.R., Slinger, S.J., Neudoerffer, T.S.
Format: Article
Language:English
Subjects:
Animal Nutritional Physiological Phenomena
Animals
Body Weight
Diet
Dietary Carbohydrates
Digestion
Energy Metabolism
Fructose - administration & dosage
Fructose - metabolism
Glucose - administration & dosage
Glucose - metabolism
Male
Rats
Structure-Activity Relationship
Sucrose - administration & dosage
Sucrose - metabolism
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Summary:A study was made of carbohydrate digestibility and weight gain response in rats fed sucrose, glucose or fructose at varying levels in the diet. In a long-term experiment with older rats, sucrose-fed animals attained a greater mature weight than glucose- and fructose-fed animals. In a digestibility study of shorter duration, animals fed sucrose and glucose diets had similar weight gains whereas fructosefed animals showed a diminished weight gain response at higher levels of fructose in the diet. The digestible energy of glucose was observed to be significantly lower than that for either sucrose or fructose. Whereas the lower digestible energy of glucose may account for the lower weight gain on high glucose diets, a similar explanation is not valid for the response to fructose feeding. It would appear that an effect other than lowered feed intake or decreased digestibility is the cause of the lower weight gains observed on high fructose diets.
ISSN:0029-6678
2571-6506