Lignans from Larrea divaricata

A phytochemical reinvestigation of the phenolics of Larrea divaricata led to the isolation and characterization of dihydroguaiaretic acid, norisoguaiacin, and 3'-demethoxyisoguaiacin. Partially demethylated dihydroguaiaretic acid was detected via the use of partially demethylated dihydroguaiare...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences 1974-12, Vol.63 (12), p.1905-1907
Main Authors: Gisvold, Ole, Thaker, Emil
Format: Article
Language:English
Subjects:
and 3′-demethoxyiso-guaiacin
and 3′-demethoxyisoguaiacin from L. divaricata
Anticancer agents
Anticancer agents, potential–isolation and characterization of dihydroguaiaretic acid, norisoguaiacin, and 3'-demethoxyisoguaiacin from L. divaricata, screening
Antioxidants - pharmacology
Bacillus subtilis - drug effects
biological screening
Chromatography, Gas
Chromatography, Thin Layer
Larrea divaricata-isolation and characterization of dihydroguaiaretic acid
Larrea divaricata–isolation and characterization of dihydroguaiaretic acid, norisoguaiacin, and 3'-demethoxyisoguaiacin, biological screening
Larrea divaricata—isolation and characterization of dihydroguaiaretic acid, norisoguaiacin, and 3′‐demethoxyiso‐guaiacin, biological screening
Lignans from L. divaricata-isolation and characterization of phenolics
Lignans from L. divaricata–isolation and characterization of phenolics, biological screening
Lignin - analogs & derivatives
Lignin - isolation & purification
Lignin - pharmacology
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
norisoguaiacin
Phenols - isolation & purification
Plants - analysis
potential-isolation and characterization of dihydroguaiaretic acid
Pseudomonas aeruginosa - drug effects
screening
Solubility
Staphylococcus - drug effects
Streptococcus - drug effects
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Summary:A phytochemical reinvestigation of the phenolics of Larrea divaricata led to the isolation and characterization of dihydroguaiaretic acid, norisoguaiacin, and 3'-demethoxyisoguaiacin. Partially demethylated dihydroguaiaretic acid was detected via the use of partially demethylated dihydroguaiaretic acid synthesized from dihydroguaiaretic acid. Techniques are given for the preparation of norisoguaiacin, dihydroguaiaretic acid, and nordihydroguaiaretic acid. Sodium molybdate complexes were used to effect the isolation and preparation of norisoguaiacin. Some biological properties of the phenolic compounds studied are given.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600631216