Viruses Associated with Epidemic Hemorrhagic Fevers of the Philippines and Thailand

Epidemiologic, clinical, and etiologic studies were carried out on a newly recognized, frequently fatal, pediatric disease syndrome which occurred in urban areas infested with Aedes aegypti mosquitoes. Four types of dengue virus (two of which are new), chikungunya virus, and another virus yet to be...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1960-04, Vol.131 (3407), p.1102-1103
Main Authors: W. Mc D. Hammon, Rudnick, A., Sather, G. E.
Format: Article
Language:English
Subjects:
Aedes
Alphavirus Infections
Animals
Chikungunya virus
Child
Communicable Diseases
Dengue
Dengue Virus
Disease etiology
Epidemics
Epidemiology
Etiology
Fetus
Fever
Hemorrhagic Fever with Renal Syndrome - virology
Hemorrhagic Fevers, Viral
Humans
Infant
Old Medline
Philippines
Placenta
Pregnancy
Thailand
Virus Diseases
Viruses
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Summary:Epidemiologic, clinical, and etiologic studies were carried out on a newly recognized, frequently fatal, pediatric disease syndrome which occurred in urban areas infested with Aedes aegypti mosquitoes. Four types of dengue virus (two of which are new), chikungunya virus, and another virus yet to be identified were isolated from the blood of patients. Dengue viruses, types 2 and 3, were isolated from the mosquitoes. Ample serologic confirmation was obtained of concurrent hemorrhagic fever and infection with one or more of these viruses. Thus, it was discovered that viruses of previously recognized types and of closely related new types apparently have etiologic roles in a new and highly dangerous epidemic disease syndrome.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.131.3407.1102