Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate

BERGER et al. reported 1 that ribonucleosides and deoxynucleosides can be differentiated by their effects on the optical spectra of copper(II) acetate in dimethylsulphoxide (DMSO). They suggested that the 2′ and 3′ oxygen atoms in ribonucleosides bridge pairs of copper atoms, forming 1 : 1 copper(II...

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Bibliographic Details
Published in:Nature (London) 1975-01, Vol.253 (5487), p.127-128
Main Authors: BRUN, G, GOODGAME, D. M. L, SKAPSKI, A. C
Format: Article
Language:English
Subjects:
Acetates
Chemical Phenomena
Chemistry
Copper
Cytidine
Deoxycytidine
Deoxyribonucleosides
Deoxyuridine
Humanities and Social Sciences
letter
multidisciplinary
Ribonucleosides
Science
Science (multidisciplinary)
Spectrum Analysis
Thymidine
Uridine
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Summary:BERGER et al. reported 1 that ribonucleosides and deoxynucleosides can be differentiated by their effects on the optical spectra of copper(II) acetate in dimethylsulphoxide (DMSO). They suggested that the 2′ and 3′ oxygen atoms in ribonucleosides bridge pairs of copper atoms, forming 1 : 1 copper(II) acetate/ribonucleoside complexes 1 . We have examined the species in such solutions by EPR. Optical spectra are not ideal as the bands are broad, and components of mixtures cannot readily be resolved. EPR spectra of spin-coupled ( S = 1) copper(II) dimers differ appreciably, however, from those of monomeric ( S = ½) compounds. Moreover, they are sensitive to the nature of the bridges 2–5 and to the symmetry about the Cu–Cu axis. Our conclusions from these studies differ from those obtained previously 1 .
ISSN:0028-0836
1476-4687
DOI:10.1038/253127a0