Stimulation of adenylate deaminase activity by serotonin

After a single intraperitoneal injection of serotonin into rats adenylate deaminase activity in the mitochondrial fraction of the liver was stimulated. The conditions under which a twofold increase in the deamination of AMP occurred, after serotonin administration,were determined. Preliminary blocki...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1975-01, Vol.77 (7), p.773-775
Main Authors: Gridneva, L I, Suvorov, N N, Gorkin, V Z
Format: Article
Language:English
Subjects:
Adenosine Monophosphate
Amidohydrolases - metabolism
Animals
Enzyme Activation
Male
Mitochondria, Liver - enzymology
Pargyline - pharmacology
Rats
Serotonin - pharmacology
Stimulation, Chemical
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Summary:After a single intraperitoneal injection of serotonin into rats adenylate deaminase activity in the mitochondrial fraction of the liver was stimulated. The conditions under which a twofold increase in the deamination of AMP occurred, after serotonin administration,were determined. Preliminary blocking of monamine oxidase activity did not prevent this effect of serotonin.
ISSN:0007-4888