Biological Disposition of Apomorphine II: Urinary Excretion and Organ Distribution of Apomorphine

A method for estimation of free and “bound” apomorphine in biologic media is described. Apomorphine, after parenteral administration to different animal species, is biotransformed and excreted in urine largely in its “bound” form. Studies on the organ-distribution of injected apomorphine in rats rev...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pharmaceutical sciences 1961-03, Vol.50 (3), p.244-247
Main Authors: Kaul, P.N., Brochmann-Hanssen, E., Way, E. Leong
Format: Article
Language:English
Subjects:
Apnea - metabolism
Apomorphine
Humans
Old Medline
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A method for estimation of free and “bound” apomorphine in biologic media is described. Apomorphine, after parenteral administration to different animal species, is biotransformed and excreted in urine largely in its “bound” form. Studies on the organ-distribution of injected apomorphine in rats revealed a localization of “bound” apomorphine in the liver.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600500316