SEROLOGIC PROFILE OF CHILDREN IN A MEXICAN HIGHLAND COMMUNITY: PREVALENCE OF COMPLEMENT-FIXING ANTIBODIES TO MYCOPLASMA PNEUMONIAE RESPIRATORY SYNCYTIAL VIRUS AND PARAINFLUENZA VIRUSES

The study investigated the prevalence of antibodies to five leading agents of childhood respiratory disease in the county of Huixquilucan, Mexico. Tests of sera from a random sample of children between 3 months and 18 years of age confirmed serologically the presence of Mycoplasma pneumoniae, respir...

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Published in:American journal of epidemiology 1975-05, Vol.101 (5), p.458-464
Main Authors: GOLUBJATNIKOV, RJURIK, ALLEN, VIRGINIA D., OLMOS-BLANCARTE, M. PILAR, INHORN, STANLEY L.
Format: Article
Language:English
Subjects:
Adolescent
Age Factors
Antibodies, Bacterial - analysis
Antibodies, Viral - analysis
Child
Child, Preschool
Complement Fixation Tests
Family Characteristics
Humans
Infant
Mexico
Mycoplasma - immunology
Mycoplasma Infections - epidemiology
Mycoplasma Infections - immunology
Mycoplasma pneumoniae
parainfluenza viruses
respiratory syncytial virus
Respiratory Syncytial Viruses - immunology
Respiratory Tract Infections - immunology
Respirovirus - immunology
Virus Diseases - epidemiology
Virus Diseases - immunology
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container_issue 5
container_start_page 458
container_title American journal of epidemiology
container_volume 101
creator GOLUBJATNIKOV, RJURIK
ALLEN, VIRGINIA D.
OLMOS-BLANCARTE, M. PILAR
INHORN, STANLEY L.
description The study investigated the prevalence of antibodies to five leading agents of childhood respiratory disease in the county of Huixquilucan, Mexico. Tests of sera from a random sample of children between 3 months and 18 years of age confirmed serologically the presence of Mycoplasma pneumoniae, respiratory syncytial (RS) virus and parainfluenza 1. 2 and 3 viruses in this relatively isolated highland community. Highest overall antibody frequency of 64.2% was seen for parainfluenza 3. and antibody to this virus was acquired early in life. Antibody to M. pneumoniae was least prevalent among children surveyed; this rate was 15.5% overall. This was only slightly below the prevalence rates for antibodies to RS virus and parainfluenza 1 and 2 viruses, which had intermediate frequency rates of 23%. 32%. and 22.9%. respectively. The relatively low prevalence of antibody to RS virus was unexpected. Differences in prevalence rates in regard to location of residence or family size were insignificant. Statistically significant differences in age-specific antibody prevalence rates in respect to sex were noted only for the 5- to 9-year-old group to M. pneumoniae and to parainfluenza 3.
doi_str_mv 10.1093/oxfordjournals.aje.a112113
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Highest overall antibody frequency of 64.2% was seen for parainfluenza 3. and antibody to this virus was acquired early in life. Antibody to M. pneumoniae was least prevalent among children surveyed; this rate was 15.5% overall. This was only slightly below the prevalence rates for antibodies to RS virus and parainfluenza 1 and 2 viruses, which had intermediate frequency rates of 23%. 32%. and 22.9%. respectively. The relatively low prevalence of antibody to RS virus was unexpected. Differences in prevalence rates in regard to location of residence or family size were insignificant. Statistically significant differences in age-specific antibody prevalence rates in respect to sex were noted only for the 5- to 9-year-old group to M. pneumoniae and to parainfluenza 3.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>165720</pmid><doi>10.1093/oxfordjournals.aje.a112113</doi><tpages>7</tpages></addata></record>
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subjects Adolescent
Age Factors
Antibodies, Bacterial - analysis
Antibodies, Viral - analysis
Child
Child, Preschool
Complement Fixation Tests
Family Characteristics
Humans
Infant
Mexico
Mycoplasma - immunology
Mycoplasma Infections - epidemiology
Mycoplasma Infections - immunology
Mycoplasma pneumoniae
parainfluenza viruses
respiratory syncytial virus
Respiratory Syncytial Viruses - immunology
Respiratory Tract Infections - immunology
Respirovirus - immunology
Virus Diseases - epidemiology
Virus Diseases - immunology
title SEROLOGIC PROFILE OF CHILDREN IN A MEXICAN HIGHLAND COMMUNITY: PREVALENCE OF COMPLEMENT-FIXING ANTIBODIES TO MYCOPLASMA PNEUMONIAE RESPIRATORY SYNCYTIAL VIRUS AND PARAINFLUENZA VIRUSES
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