Deoxyribonucleic Acid Structures in the Nucleolus

PHASE-CONTRAST observation and electron microscopy indicate that the nucleolus is structurally heterogeneous consisting of a ground material in which is embedded a more compactly aggregated material generally described as filamentous (Estable and Sotelo 1 proposed for them the names of ‘pars amorpha...

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Bibliographic Details
Published in:Nature (London) 1961-09, Vol.191 (4795), p.1325-1326
Main Author: O'DONNELL, ELSA H. J
Format: Article
Language:English
Subjects:
Cell Nucleolus
Cell Nucleus - chemistry
DNA - chemistry
Humanities and Social Sciences
letter
multidisciplinary
Old Medline
Science
Science (multidisciplinary)
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Summary:PHASE-CONTRAST observation and electron microscopy indicate that the nucleolus is structurally heterogeneous consisting of a ground material in which is embedded a more compactly aggregated material generally described as filamentous (Estable and Sotelo 1 proposed for them the names of ‘pars amorpha’ and ‘nucleolonema’). Nucleoli of plant and animal cells are seen at mitosis and meiosis associated with a particular chromosome or chromosomes—the so-called ‘nucleolar organizer’ chromosomes—at the site of a heterochromatic region. If a chromosomal deletion includes such a region or if a mutation occurs 2 , nucleolar material is then produced at other ‘loci’ (the latent organizers).
ISSN:0028-0836
1476-4687
DOI:10.1038/1911325a0