Relationship between changes of serum cholecystokinin-pancreozymin and serum insulin after different stimuli

The relationship between changes of serum immuno-reactive cholecystokinin-pancreozymin (CCK-PZ) and serum immuno-reactive insulin has been studied after various stimuli. The oral administration of 5 percent glucose or magnesium sulphate and the intra-duodenal administration of olive oil were all fol...

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Bibliographic Details
Published in:Diabetologia 1975-02, Vol.11 (1), p.35-38
Main Authors: Grayburn, J A, Harvey, R F, Jennings, R D, Dowsett, L, Hartog, M
Format: Article
Language:English
Subjects:
Adult
Blood Glucose - analysis
Cholecystokinin - blood
Fasting
Female
Glucose
Humans
Insulin - blood
Magnesium Sulfate
Male
Oils
Radioimmunoassay
Stimulation, Chemical
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Summary:The relationship between changes of serum immuno-reactive cholecystokinin-pancreozymin (CCK-PZ) and serum immuno-reactive insulin has been studied after various stimuli. The oral administration of 5 percent glucose or magnesium sulphate and the intra-duodenal administration of olive oil were all followed by a rise of serum CCK-PZ. The serum insulin rose after 5 percent glucose and also showed a small but insignificant rise with olive oil. There was, however, no change of serum insulin after the ingestion of magnesium sulphate suggesting that CCK-PZ in isolation does not stimulate insulin release.
ISSN:0012-186X
1432-0428
DOI:10.1007/BF00422815