A COMPARISON OF CHLORMETHIAZOLE AND DIAZEPAM AS INTRAVENOUS SEDATIVES FOR FIBRE-ENDOSCOPIC EXAMINATION OF THE UPPER GASTROINTESTINAL TRACT

Chlormethiazole and diazepam as intravenous sedatives were compared in 75 patients undergoing fibre-endoscopic examination of the upper gastrointestinal tract. Diazepam was considered to offer greater reliability and ease of administration. Chlormethiazole was found to be a safe drug and did not enc...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1975-03, Vol.47 (3), p.402-407
Main Authors: GALIZIA, E.J., METREWELI, C., PROUT, B.J.
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Blood Pressure - drug effects
Chlormethiazole - pharmacology
Diazepam - pharmacology
Dose-Response Relationship, Drug
Electrocardiography
Endoscopy
Female
Fiber Optic Technology
Hemolysis
Humans
Hypnotics and Sedatives
Inhalation
Injections, Intravenous
Intestines
Lung
Male
Middle Aged
Pulse - drug effects
Stomach
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Description
Summary:Chlormethiazole and diazepam as intravenous sedatives were compared in 75 patients undergoing fibre-endoscopic examination of the upper gastrointestinal tract. Diazepam was considered to offer greater reliability and ease of administration. Chlormethiazole was found to be a safe drug and did not encourage salivation. Local pain caused by chlormethiazole injection can be abolished by the use of lignocaine. Chlormethiazole may be useful in patients who are hypotensive and who require emergency endoscopy.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/47.3.402