A STUDY OF THE CHANGES IN SERUM POTASSIUM CONCENTRATION WITH SUXAMETHONIUM USING DIFFERENT ANAESTHETIC AGENTS

Serum potassium concentrations were measured after administration of suxamethonium (1 mg\kg body wt.) in 101 patients in whom anaesthesia was induced by one of five different techniques. There was a maximum increase in serum potassium of 21.4% following induction with trichloroethylene compared with...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1975-04, Vol.47 (4), p.516-519
Main Authors: DHANARAJ, V.J., NARAYANAMURTHY, J., SITADEVI, C., RAO, K. MOHAN
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anesthesia, General
Child
Child, Preschool
Chloroform
Ether
Female
Halothane
Humans
Male
Middle Aged
Nitrous Oxide
Oxygen
Potassium - blood
Succinylcholine - pharmacology
Thiopental
Trichloroethylene
Tubocurarine
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Summary:Serum potassium concentrations were measured after administration of suxamethonium (1 mg\kg body wt.) in 101 patients in whom anaesthesia was induced by one of five different techniques. There was a maximum increase in serum potassium of 21.4% following induction with trichloroethylene compared with 4.4% with nitrous oxide\oxygen. There were only small increaes in serum potassium with halothane and chloroform. In an additional 10 patients who received tubocurarine (3 mg) before induction of anaesthesia with thiopentone, the maximum increase in serum potassium was 10.6% following suxamethonium. It is concluded that the increase in serum potassium following induction of anaesthesia is the result of a combined effect of the anaesthetic agent and suxamethonium.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/47.4.516