The effect of amniotic fluid removal on pulmonary maturation in sheep

Removal of amniotic fluid and the production of oligohydramnios in the pregnant ewe failed to accelerate pulmonary maturation in the fetal lamb. If further human studies confirm that the PROM induces pulmonary maturation, a third event, perhaps release of a mediator that causes both spontaneous PROM...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1975-09, Vol.56 (3), p.474-476
Main Author: Frantz, I D
Format: Article
Language:English
Subjects:
Amniotic Fluid
Animals
Drainage
Female
Fetal Membranes, Premature Rupture
Gestational Age
Humans
Infant, Newborn
Lung - embryology
Pregnancy
Respiratory Distress Syndrome, Newborn
Sheep - embryology
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Summary:Removal of amniotic fluid and the production of oligohydramnios in the pregnant ewe failed to accelerate pulmonary maturation in the fetal lamb. If further human studies confirm that the PROM induces pulmonary maturation, a third event, perhaps release of a mediator that causes both spontaneous PROM and pulmonary maturation, must be postulated.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.56.3.474