Changes in the Subcellular Distribution of Cardiac Catecholamines in Dogs dying in Irreversible Hæmorrhagic Shock

THE work of Schlossberg and Sawyer 1 has established the fact that the reactivity of the sympatho adrenal system of an animal is involved in stress situations such as severe loss of blood. Indeed, vasoconstriction due to increased peripheral sympathetic tone and elevation of circulating catecholamin...

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Bibliographic Details
Published in:Nature (London) 1962-11, Vol.196 (4855), p.678-679
Main Authors: HIFT, HELEN, CAMPOS, H. A
Format: Article
Language:English
Subjects:
Animals
Catecholamines
Dogs
Epinephrine
Heart
Humanities and Social Sciences
letter
multidisciplinary
Myocardium
Norepinephrine
Old Medline
Science
Science (multidisciplinary)
Shock
Shock, Hemorrhagic
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Summary:THE work of Schlossberg and Sawyer 1 has established the fact that the reactivity of the sympatho adrenal system of an animal is involved in stress situations such as severe loss of blood. Indeed, vasoconstriction due to increased peripheral sympathetic tone and elevation of circulating catecholamines resulting from the stimulation of the adrenal medulla by the sympathetic centres are outstanding signs of hypovolemic hypotension. In experimental hæmorrhagic shock increased blood-levels of epinephrine and norepinephrine have most recently been reported by Greever and Watts 2 and Walker and co-workers 3,4 .
ISSN:0028-0836
1476-4687
DOI:10.1038/196678b0