Isolation and Identification of Three New Flavones from Achillea millefolium L

Column chromatography on silica gel of a petroleum ether extract of the flowering heads of Achillea millefolium L. allowed three flavones to be separated and identified. Spectral studies (PMR, mass spectrometry, and UV) and a comparison with data for compounds reported in the literature established...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences 1975-11, Vol.64 (11), p.1838-1842
Main Authors: Falk, A.J., Smolenski, S.J., Bauer, L., Bell, C.L.
Format: Article
Language:English
Subjects:
Achillea millefolium-chromatographic isolation and spectral identification of flavone components
Flavones-chromatographic separation and spectral identification from Achillea millefolium
Flavonoids - analysis
Flavonoids - isolation & purification
isolation and identification of flavone components
Mass Spectrometry
Medicinal plants-Achillea millefolium
Medicinal plants—Achillea millefolium, isolation and identification of flavone components
Plants, Medicinal - analysis
Spectrophotometry, Ultraviolet
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Summary:Column chromatography on silica gel of a petroleum ether extract of the flowering heads of Achillea millefolium L. allowed three flavones to be separated and identified. Spectral studies (PMR, mass spectrometry, and UV) and a comparison with data for compounds reported in the literature established the flavones as 5-hydroxy-3,6,7,4′-tetramethoxyflavone, artemetin, and casticin. These compounds have not been reported previously as constituents of A. millefolium.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600641119