Occurrence of Leukemia and Lymphoma in Patients with Agammaglobulinemia

1) Two case reports of children with congenital agammaglobulinemia who later developed malignant lymphoma are presented. 2) Two additional cases of malignant lymphoma developing in adult patients with hypogammaglobulinemia are reviewed. 3) The occurrence of diseases of this group among patients with...

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Bibliographic Details
Published in:Blood 1963-02, Vol.21 (2), p.197-206
Main Authors: Page, Arthur R., Hansen, Arild E., Good, Robert A.
Format: Article
Language:English
Subjects:
Agammaglobulinemia
Leukemia
Leukemia, Lymphoid
Lymphocytes
Lymphoma
Old Medline
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Summary:1) Two case reports of children with congenital agammaglobulinemia who later developed malignant lymphoma are presented. 2) Two additional cases of malignant lymphoma developing in adult patients with hypogammaglobulinemia are reviewed. 3) The occurrence of diseases of this group among patients with this immunologic defect appears to be a greater-than-chance association. Possible reasons for the association are discussed.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V21.2.197.197