Biological activity of hydroxyanthraquinones and their glucosides toward microorganisms

Five mono- and dihydroxyanthraquinones as well as 12 of their glucosides (both free and acetylated) were tested with six different microbial species using the plate-diffusion method. None of the tested substances was active against Escherichia coli, 15 of the 17 substances displayed an activity towa...

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Bibliographic Details
Published in:Folia microbiologica 1976, Vol.21 (1), p.54-57
Main Authors: Cudlin, J, Blumauerova, M, Steinerova, N, Mateju, J, Zalabak, V
Format: Article
Language:English
Subjects:
Anthraquinones - metabolism
Anthraquinones - pharmacology
Bacillus cereus - drug effects
Bacillus subtilis - drug effects
Bacteria - drug effects
Candida albicans - drug effects
Chemical Phenomena
Chemistry
Escherichia coli - drug effects
Fungi - drug effects
Glucosides - pharmacology
Glycosides - pharmacology
plant biochemistry
plant physiology
Saccharomyces cerevisiae - drug effects
Streptomyces aureofaciens - drug effects
Streptomyces aureofaciens - metabolism
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Summary:Five mono- and dihydroxyanthraquinones as well as 12 of their glucosides (both free and acetylated) were tested with six different microbial species using the plate-diffusion method. None of the tested substances was active against Escherichia coli, 15 of the 17 substances displayed an activity toward Bacillus subtilis, Bacillus cereus, Candida albicans, Saccharomyces cerevisiae and Streptomyces aureofaciens. Relationships between the substance type and biological activity are discussed.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF02879007