Interaction of Chromatid Breaks induced by Three Different Radiomimetic Compounds

QUITE a few physical and chemical inducers of chromosomal aberrations have been tested for interaction of chromatid breaks induced by different agents, the product of interaction being chromatid translocations (exchanges). On the basis of the breakage-reunion hypothesis presence or absence of intera...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 1963-09, Vol.199 (4897), p.1014-1015
Main Authors: MICHAELIS, ARND, RIEGER, RIGOMAR
Format: Article
Language:English
Subjects:
Antineoplastic Agents
Chromatids
Chromosomes
Ethanol
Heterocyclic Compounds
Humanities and Social Sciences
letter
multidisciplinary
Old Medline
Pharmacology
Plants, Medicinal
Science
Science (multidisciplinary)
Triethylenemelamine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:QUITE a few physical and chemical inducers of chromosomal aberrations have been tested for interaction of chromatid breaks induced by different agents, the product of interaction being chromatid translocations (exchanges). On the basis of the breakage-reunion hypothesis presence or absence of interaction may be expected to give some hints on the bonds broken by the treatments being identical (full interaction) or not (no interaction, additive effect), provided time (different stages of maximal sensitivity against the agents) and space factors (different distribution of aberrations within and between chromosomes) can be ruled out as influencing the experimental results.
ISSN:0028-0836
1476-4687
DOI:10.1038/1991014a0