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Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning
the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations. to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, com...
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| Published in: | Arquivos brasileiros de cardiologia 2010-10, Vol.95 (4), p.486-492 |
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| container_end_page | 492 |
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| container_title | Arquivos brasileiros de cardiologia |
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| creator | Uchida, Augusto Moffa, Paulo Hueb, Whady Cesar, Luiz Antonio Machado Ferreira, Beatriz Moreira Ayub Ramires, Jose Antonio Franchini |
| description | the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations.
to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, comparing it to the conventional T-1.0 mm index.
sixty one patients with mean age of 62.2 ± 7.5 years were evaluated; 86.9% were males. A total of 151 tests were analyzed, 116 of which were from patients who completed two assessment phases. The first phase comprised two sequential exercise tests for the documentation of IPC; the second phase, initiated one week later, comprised two more tests carried out under the effect of repaglinide. Two observers who were blind to the tests applied the score.
Perfect inter and intraobserver agreement was found (Kendall tau-b = 0.96, p < 0.0001, and Kendall tau-b = 0.98, p < 0.0001, respectively). Values of sensitivity and specificity, negative predictive value, positive predictive value and accuracy were 72.41%, 89.29%, 75.8%, 87.5% and 81.0%, respectively.
the ischemic score is a consistent and reproducible method for the documentation of IPC, and is a feasible alternative to T-1.0 mm. |
| doi_str_mv | 10.1590/s0066-782x2010005000122 |
| format | article |
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to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, comparing it to the conventional T-1.0 mm index.
sixty one patients with mean age of 62.2 ± 7.5 years were evaluated; 86.9% were males. A total of 151 tests were analyzed, 116 of which were from patients who completed two assessment phases. The first phase comprised two sequential exercise tests for the documentation of IPC; the second phase, initiated one week later, comprised two more tests carried out under the effect of repaglinide. Two observers who were blind to the tests applied the score.
Perfect inter and intraobserver agreement was found (Kendall tau-b = 0.96, p < 0.0001, and Kendall tau-b = 0.98, p < 0.0001, respectively). Values of sensitivity and specificity, negative predictive value, positive predictive value and accuracy were 72.41%, 89.29%, 75.8%, 87.5% and 81.0%, respectively.
the ischemic score is a consistent and reproducible method for the documentation of IPC, and is a feasible alternative to T-1.0 mm.</description><identifier>EISSN: 1678-4170</identifier><identifier>DOI: 10.1590/s0066-782x2010005000122</identifier><identifier>PMID: 20835683</identifier><language>eng</language><publisher>Brazil</publisher><subject>Carbamates ; Diabetes Mellitus - drug therapy ; Diabetes Mellitus - physiopathology ; Double-Blind Method ; Electrocardiography - methods ; Electrocardiography - standards ; Ergometry ; Female ; Humans ; Hypoglycemic Agents - therapeutic use ; Ischemic Preconditioning ; Male ; Middle Aged ; Myocardial Ischemia - diagnosis ; Observer Variation ; Piperidines ; Predictive Value of Tests</subject><ispartof>Arquivos brasileiros de cardiologia, 2010-10, Vol.95 (4), p.486-492</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20835683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Uchida, Augusto</creatorcontrib><creatorcontrib>Moffa, Paulo</creatorcontrib><creatorcontrib>Hueb, Whady</creatorcontrib><creatorcontrib>Cesar, Luiz Antonio Machado</creatorcontrib><creatorcontrib>Ferreira, Beatriz Moreira Ayub</creatorcontrib><creatorcontrib>Ramires, Jose Antonio Franchini</creatorcontrib><title>Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning</title><title>Arquivos brasileiros de cardiologia</title><addtitle>Arq Bras Cardiol</addtitle><description>the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations.
to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, comparing it to the conventional T-1.0 mm index.
sixty one patients with mean age of 62.2 ± 7.5 years were evaluated; 86.9% were males. A total of 151 tests were analyzed, 116 of which were from patients who completed two assessment phases. The first phase comprised two sequential exercise tests for the documentation of IPC; the second phase, initiated one week later, comprised two more tests carried out under the effect of repaglinide. Two observers who were blind to the tests applied the score.
Perfect inter and intraobserver agreement was found (Kendall tau-b = 0.96, p < 0.0001, and Kendall tau-b = 0.98, p < 0.0001, respectively). Values of sensitivity and specificity, negative predictive value, positive predictive value and accuracy were 72.41%, 89.29%, 75.8%, 87.5% and 81.0%, respectively.
the ischemic score is a consistent and reproducible method for the documentation of IPC, and is a feasible alternative to T-1.0 mm.</description><subject>Carbamates</subject><subject>Diabetes Mellitus - drug therapy</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Double-Blind Method</subject><subject>Electrocardiography - methods</subject><subject>Electrocardiography - standards</subject><subject>Ergometry</subject><subject>Female</subject><subject>Humans</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>Ischemic Preconditioning</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Ischemia - diagnosis</subject><subject>Observer Variation</subject><subject>Piperidines</subject><subject>Predictive Value of Tests</subject><issn>1678-4170</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNo1UEtPwzAYi5AQG4O_ALlxKuTRpCk3NPGSJnGBc5WkX7agtilJJo1_TxDjYPliW7YRuqbkloqW3CVCpKwaxQ6MUEKIKKCMnaAllY2qatqQBTpP6ZMQxhouztCCEcWFVHyJto8D2ByD1bH3YRv1vPMWJxsi3GM9z4O3OvswYT9hOEC0PgHOkDJ2IeK8A6xTgpRGmDIODvtkdzCWiDmCDVPvf81-2l6gU6eHBJdHXqGPp8f39Uu1eXt-XT9sqplRkitbU-u0aYHwVraMql4Kp52swRpH66apqbC9EUxwZZmWynFLuTJGOENbCXyFbv5y5xi-9qVnN5ZKMAx6grBPXdlNyy0tL8qro3JvRui7OfpRx-_u_xv-A9fyaHg</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>Uchida, Augusto</creator><creator>Moffa, Paulo</creator><creator>Hueb, Whady</creator><creator>Cesar, Luiz Antonio Machado</creator><creator>Ferreira, Beatriz Moreira Ayub</creator><creator>Ramires, Jose Antonio Franchini</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201010</creationdate><title>Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning</title><author>Uchida, Augusto ; Moffa, Paulo ; Hueb, Whady ; Cesar, Luiz Antonio Machado ; Ferreira, Beatriz Moreira Ayub ; Ramires, Jose Antonio Franchini</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p210t-c41cfab9e03969218d65faf64ecbf1477415cdb52538c2a68f3c138bb5fb196e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Carbamates</topic><topic>Diabetes Mellitus - drug therapy</topic><topic>Diabetes Mellitus - physiopathology</topic><topic>Double-Blind Method</topic><topic>Electrocardiography - methods</topic><topic>Electrocardiography - standards</topic><topic>Ergometry</topic><topic>Female</topic><topic>Humans</topic><topic>Hypoglycemic Agents - therapeutic use</topic><topic>Ischemic Preconditioning</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Ischemia - diagnosis</topic><topic>Observer Variation</topic><topic>Piperidines</topic><topic>Predictive Value of Tests</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Uchida, Augusto</creatorcontrib><creatorcontrib>Moffa, Paulo</creatorcontrib><creatorcontrib>Hueb, Whady</creatorcontrib><creatorcontrib>Cesar, Luiz Antonio Machado</creatorcontrib><creatorcontrib>Ferreira, Beatriz Moreira Ayub</creatorcontrib><creatorcontrib>Ramires, Jose Antonio Franchini</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Arquivos brasileiros de cardiologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Uchida, Augusto</au><au>Moffa, Paulo</au><au>Hueb, Whady</au><au>Cesar, Luiz Antonio Machado</au><au>Ferreira, Beatriz Moreira Ayub</au><au>Ramires, Jose Antonio Franchini</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning</atitle><jtitle>Arquivos brasileiros de cardiologia</jtitle><addtitle>Arq Bras Cardiol</addtitle><date>2010-10</date><risdate>2010</risdate><volume>95</volume><issue>4</issue><spage>486</spage><epage>492</epage><pages>486-492</pages><eissn>1678-4170</eissn><abstract>the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations.
to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, comparing it to the conventional T-1.0 mm index.
sixty one patients with mean age of 62.2 ± 7.5 years were evaluated; 86.9% were males. A total of 151 tests were analyzed, 116 of which were from patients who completed two assessment phases. The first phase comprised two sequential exercise tests for the documentation of IPC; the second phase, initiated one week later, comprised two more tests carried out under the effect of repaglinide. Two observers who were blind to the tests applied the score.
Perfect inter and intraobserver agreement was found (Kendall tau-b = 0.96, p < 0.0001, and Kendall tau-b = 0.98, p < 0.0001, respectively). Values of sensitivity and specificity, negative predictive value, positive predictive value and accuracy were 72.41%, 89.29%, 75.8%, 87.5% and 81.0%, respectively.
the ischemic score is a consistent and reproducible method for the documentation of IPC, and is a feasible alternative to T-1.0 mm.</abstract><cop>Brazil</cop><pmid>20835683</pmid><doi>10.1590/s0066-782x2010005000122</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | EISSN: 1678-4170 |
| ispartof | Arquivos brasileiros de cardiologia, 2010-10, Vol.95 (4), p.486-492 |
| issn | 1678-4170 |
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| subjects | Carbamates Diabetes Mellitus - drug therapy Diabetes Mellitus - physiopathology Double-Blind Method Electrocardiography - methods Electrocardiography - standards Ergometry Female Humans Hypoglycemic Agents - therapeutic use Ischemic Preconditioning Male Middle Aged Myocardial Ischemia - diagnosis Observer Variation Piperidines Predictive Value of Tests |
| title | Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning |
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