Action of caerulein, glucagon or prostaglandin E1 on the motility of intestinal villi

If injected into the artery supplying the first jejunal loop of dogs, caerulein increases, glucagon and PGE-1 decrease villous motility significantly. The relationship between the natural logarithm of the drug doses and their effects is linear.

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Bibliographic Details
Published in:Pflügers Archiv 1976-08, Vol.364 (3), p.301-304
Main Authors: Ihász, M, Koiss, I, Németh, E P, Folly, G, Papp, M
Format: Article
Language:English
Subjects:
Animals
Ceruletide - pharmacology
Dogs
Dose-Response Relationship, Drug
Gastrointestinal Motility - drug effects
Glucagon - pharmacology
Male
Prostaglandins E - pharmacology
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Description
Summary:If injected into the artery supplying the first jejunal loop of dogs, caerulein increases, glucagon and PGE-1 decrease villous motility significantly. The relationship between the natural logarithm of the drug doses and their effects is linear.
ISSN:0031-6768
1432-2013
DOI:10.1007/BF00581769