PULMONARY ARTERY STENOSIS ASSOCIATED WITH DUCTUS ARTERIOSUS FOLLOWING MATERNAL RUBELLA

Nine patients with pulmonary artery stenosis associated with patent ductus arteriosus following maternal rubella are described. Five of the patients had bilateral pulmonary artery stenosis and four cases involved only the right pulmonary artery. Mild pulmonary valvular stenosis was present in five a...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1964-04, Vol.29 (4), p.SUPPL:514-522
Main Authors: EMMANOUILIDES, G C, LINDE, L M, CRITTENDEN, I H
Format: Article
Language:English
Subjects:
Angiocardiography
Cardiac Catheterization
Cataract
Constriction, Pathologic
Deafness
Ductus Arteriosus
Ductus Arteriosus, Patent
Female
Fetal Diseases
Heart Septal Defects
Heart Septal Defects, Ventricular
Humans
Hypertension
Hypertension, Pulmonary
Infant
Infant, Newborn
Infant, Premature, Diseases
Maternal-Fetal Exchange
Old Medline
Pregnancy
Pregnancy Complications, Infectious
Pulmonary Artery
Pulmonary Valve Stenosis
Rubella
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Summary:Nine patients with pulmonary artery stenosis associated with patent ductus arteriosus following maternal rubella are described. Five of the patients had bilateral pulmonary artery stenosis and four cases involved only the right pulmonary artery. Mild pulmonary valvular stenosis was present in five and a ventricular septal defect in one. The persistence of a systolic murmur transmitted to the lateral chest wall, after ligation or division of a patent ductus arteriosus, should arouse suspicion of the presence of pulmonary artery stenosis. This report supports the recently described implication of maternal rubella as a cause of pulmonary artery stenosis. Careful auscultation in patients with history of maternal rubella may discover the presence of such an arterial anomaly, but cardiac catheterization and angiocardiography are necessary for substantiation of diagnosis. The natural history of these lesions is not known.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.29.4.514