Antigens Associated with a Tumor Virus: Rejection of Isogenic Skin Grafts from Leukemic Mice

Skin grafts from leukemic adult Balb/c mice inoculated when newborn with a leukemia virus, showed evidence of rejection when transplanted to normal Balb/c mice or genetically compatible F$_{1}$ hybrids. Therefore, the "cellular" antigens associated with oncogenic viruses may not be limited...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1964-11, Vol.146 (3647), p.1055-1056
Main Authors: Breyere, Edward J., Williams, Louis B.
Format: Article
Language:English
Subjects:
Animals
Antigens
Cell walls
Graft rejection
Hybridity
Infections
Leukemia
Leukemia, Experimental
Mice
Mice, Inbred BALB C
Neoplasms
Old Medline
Oncogenic Viruses
Skin grafts
Skin Transplantation
Tissue grafting
Transplantation, Homologous
Tumors
Viruses
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Description
Summary:Skin grafts from leukemic adult Balb/c mice inoculated when newborn with a leukemia virus, showed evidence of rejection when transplanted to normal Balb/c mice or genetically compatible F$_{1}$ hybrids. Therefore, the "cellular" antigens associated with oncogenic viruses may not be limited to the induced tumors.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.146.3647.1055