Origin of Urinary Resorcinol Sulphate

SOME human subjects have been shown to excrete large amounts of urinary resorcinol monosulphate ester 1 . This appears on paper chromatograms as a magenta spot after spraying with 2 per cent p -dimethylaminobenz-aldehyde in 5 per cent v/v concentrated hydrochloric acid and heating at 55° C for 12–15...

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Bibliographic Details
Published in:Nature (London) 1964-10, Vol.204 (4956), p.383-384
Main Authors: CURZON, G, PRATT, R. T. C
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Chromatography
Drug Therapy
Humanities and Social Sciences
Humans
Intestines - microbiology
letter
Metabolism
multidisciplinary
Old Medline
Resorcinols
Schizophrenia
Science
Science (multidisciplinary)
Sulfates
Tea
Urine
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Summary:SOME human subjects have been shown to excrete large amounts of urinary resorcinol monosulphate ester 1 . This appears on paper chromatograms as a magenta spot after spraying with 2 per cent p -dimethylaminobenz-aldehyde in 5 per cent v/v concentrated hydrochloric acid and heating at 55° C for 12–15 min. (The sensitivity of resorcinol sulphate to this reagent at room temperature is much lower and the resultant colour is grey.) The spot runs rather more slowly than indoxyl sulphate in iso-propanol–0.880 ammonia–water ; 20 : 1 : 2 ( R F 0.50, 0.60 respectively), and also in n -butanol–acetic acid–water; 12 : 3 : 5 ( R F 0.42, 0.46).
ISSN:0028-0836
1476-4687
DOI:10.1038/204383a0