Synthesis and enzymatic activity of an RNase S′ analogue in which the 4-imidazolylglycyl residue takes the position and the role of histidine-12

• Published in: FEBS letters 1976-10, Vol.68 (2), p.228-230
• Main Authors: van Batenburg, O.D., Kerling, K.E.T., Havinga, E.
• Format: Article
• Language: English
• Subjects: Animals; bovine pancreatic ribonuclease; Cattle; Glycine; Histidine; Imidazoles; Kinetics; native ribonuclease cleaved by subtilisin; Pancreas - enzymology; Peptides - chemical synthesis; Peptides - metabolism; Ribonucleases - metabolism; RNase A; RNase S; RNase S′, the reconstituted active complex obtained by mixing equimolar amounts of S-peptide and S-protein; the resulting active complex can be separated into its two inactive components: S-peptide and S-protein
• ISSN: 0014-5793; 1873-3468
• DOI: 10.1016/0014-5793(76)80442-5