Lymphographic evaluation of 250 patients with malignant melanoma

Foot lymphography was performed in a selected group of 250 patients with malignant melanoma, with different sites of origin and of various stages. The overall incidence of metastases was 40%. The case material was evaluated in detail; the tumors of the inferior limb and those on different sites, e.g...

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Bibliographic Details
Published in:Cancer 1976-10, Vol.38 (4), p.1568-1573
Main Authors: Musumeci, R., Monica, G. La, Orefice, S., Paolucci, R., Petrillo, R., Uslenghi, C.
Format: Article
Language:English
Subjects:
Evaluation Studies as Topic
Female
Humans
Lymphatic Metastasis - diagnostic imaging
Lymphography
Male
Melanoma - diagnostic imaging
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Summary:Foot lymphography was performed in a selected group of 250 patients with malignant melanoma, with different sites of origin and of various stages. The overall incidence of metastases was 40%. The case material was evaluated in detail; the tumors of the inferior limb and those on different sites, e.g., vulva and abdomen, were considered separately. In the group of 188 patients with melanoma of the inferior limb, the incidence of metastases was 42%. In 51%, histologic confirmation was obtained. In the group of 62 patients with melanoma of different sites of the body, the incidence of metastases was 34% and histologic confirmation was obtained in 21 patients. The values of accuracy, sensitivity, and specificity based on the histologic confirmation of the lymphographic reports ranged from 88% to 96%. These data justify the use of lymphography in the initial diagnostic work‐up and in the follow‐up of these patients.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197610)38:4<1568::AID-CNCR2820380420>3.0.CO;2-O