SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS

The records of the New England Regional Infant Cardiac Program, a service program covering all of New England, provide a useful source of information about the characteristics of children born with congenital heart defects. Data were analyzed on more than 2000 children born in New England who were d...

Full description

Saved in:
Bibliographic Details
Published in:American journal of epidemiology 1976-11, Vol.104 (5), p.527-534
Main Authors: ROTHMAN, KENNETH J., FYLER, DONALD C.
Format: Article
Language:English
Subjects:
Adult
aortic diseases
aortic valve stenosis
arterio-venous fistula
Birth Order
congenital
Ductus Arteriosus, Patent
Female
heart defects
Heart Defects, Congenital - epidemiology
Heart Septal Defects, Atrial
Humans
Male
Maternal Age
New England
Pregnancy
Sex Factors
Transposition of Great Vessels
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c431t-74750324ec8c21f450670214229d23a83963ae3b4fd72d3866d72c884f5246703
cites
container_end_page 534
container_issue 5
container_start_page 527
container_title American journal of epidemiology
container_volume 104
creator ROTHMAN, KENNETH J.
FYLER, DONALD C.
description The records of the New England Regional Infant Cardiac Program, a service program covering all of New England, provide a useful source of information about the characteristics of children born with congenital heart defects. Data were analyzed on more than 2000 children born in New England who were diagnosed with a congenital heart defect before the first birthday. Children with arterio-venous fistula, aortic stenosis, transposition of the great arteries or hypoplastic left ventricle were predominantly male; children with persistent ductus arteriosus and endocardial cushion defect were predominantly female. Positive trends in risk with increasing birth order were present for pulmonic stenosis and transposition of the great arteries, and a negative trend was seen for persistent ductus arteriosus. What evidence there was for associations with maternal age was greatly reduced after controlling for confounding by birth order.
doi_str_mv 10.1093/oxfordjournals.aje.a112326
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_83612147</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1306653414</sourcerecordid><originalsourceid>FETCH-LOGICAL-c431t-74750324ec8c21f450670214229d23a83963ae3b4fd72d3866d72c884f5246703</originalsourceid><addsrcrecordid>eNpdkF1P2zAUhq1psHWwf7ALa0i7aoq_YifceanTRJQUJdlabRdWSByppSUQt1L59zNqhwRXR_L7vMdHDwDfMRphFNLLbt92fbPqdv1DtbajamVGFcaEEv4BDDAT3OPE5x_BACFEvJBw8hl8sXaFEMahjz6B0zBgiIgB-FuoxRD-TPMygbN8rPIhlNkY3shS5ZmcQjlRMEpkLiP3kBZlGhVwFsM0i2VWFnCeul40yyYqS0uHJ0rmJRyrWEVlcQ5OWnee-XqcZ-BXrMoo8aazSRrJqVczireeYMJHlDBTBzXBLfMRF4hgRkjYEFoFNOS0MvSOtY0gDQ04d7MOAtb6hDmUnoEfh72Pffe0M3arN0tbm_W6ejDdzuqAcuz2CQdevAP_K9SYIs59yjBz1NWBqvvO2t60-rFfbqr-WWOkX_Trt_q106-P-l352_GL3d3GNK_Vg28Xe4d4abdm_5pW_b3mggpfJ4s_OkZ4nvu_b_U1_QftGItg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1306653414</pqid></control><display><type>article</type><title>SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS</title><source>Oxford University Press Archive</source><creator>ROTHMAN, KENNETH J. ; FYLER, DONALD C.</creator><creatorcontrib>ROTHMAN, KENNETH J. ; FYLER, DONALD C.</creatorcontrib><description>The records of the New England Regional Infant Cardiac Program, a service program covering all of New England, provide a useful source of information about the characteristics of children born with congenital heart defects. Data were analyzed on more than 2000 children born in New England who were diagnosed with a congenital heart defect before the first birthday. Children with arterio-venous fistula, aortic stenosis, transposition of the great arteries or hypoplastic left ventricle were predominantly male; children with persistent ductus arteriosus and endocardial cushion defect were predominantly female. Positive trends in risk with increasing birth order were present for pulmonic stenosis and transposition of the great arteries, and a negative trend was seen for persistent ductus arteriosus. What evidence there was for associations with maternal age was greatly reduced after controlling for confounding by birth order.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>DOI: 10.1093/oxfordjournals.aje.a112326</identifier><identifier>PMID: 984027</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Adult ; aortic diseases ; aortic valve stenosis ; arterio-venous fistula ; Birth Order ; congenital ; Ductus Arteriosus, Patent ; Female ; heart defects ; Heart Defects, Congenital - epidemiology ; Heart Septal Defects, Atrial ; Humans ; Male ; Maternal Age ; New England ; Pregnancy ; Sex Factors ; Transposition of Great Vessels</subject><ispartof>American journal of epidemiology, 1976-11, Vol.104 (5), p.527-534</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-74750324ec8c21f450670214229d23a83963ae3b4fd72d3866d72c884f5246703</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/984027$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ROTHMAN, KENNETH J.</creatorcontrib><creatorcontrib>FYLER, DONALD C.</creatorcontrib><title>SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS</title><title>American journal of epidemiology</title><addtitle>Am J Epidemiol</addtitle><description>The records of the New England Regional Infant Cardiac Program, a service program covering all of New England, provide a useful source of information about the characteristics of children born with congenital heart defects. Data were analyzed on more than 2000 children born in New England who were diagnosed with a congenital heart defect before the first birthday. Children with arterio-venous fistula, aortic stenosis, transposition of the great arteries or hypoplastic left ventricle were predominantly male; children with persistent ductus arteriosus and endocardial cushion defect were predominantly female. Positive trends in risk with increasing birth order were present for pulmonic stenosis and transposition of the great arteries, and a negative trend was seen for persistent ductus arteriosus. What evidence there was for associations with maternal age was greatly reduced after controlling for confounding by birth order.</description><subject>Adult</subject><subject>aortic diseases</subject><subject>aortic valve stenosis</subject><subject>arterio-venous fistula</subject><subject>Birth Order</subject><subject>congenital</subject><subject>Ductus Arteriosus, Patent</subject><subject>Female</subject><subject>heart defects</subject><subject>Heart Defects, Congenital - epidemiology</subject><subject>Heart Septal Defects, Atrial</subject><subject>Humans</subject><subject>Male</subject><subject>Maternal Age</subject><subject>New England</subject><subject>Pregnancy</subject><subject>Sex Factors</subject><subject>Transposition of Great Vessels</subject><issn>0002-9262</issn><issn>1476-6256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><recordid>eNpdkF1P2zAUhq1psHWwf7ALa0i7aoq_YifceanTRJQUJdlabRdWSByppSUQt1L59zNqhwRXR_L7vMdHDwDfMRphFNLLbt92fbPqdv1DtbajamVGFcaEEv4BDDAT3OPE5x_BACFEvJBw8hl8sXaFEMahjz6B0zBgiIgB-FuoxRD-TPMygbN8rPIhlNkY3shS5ZmcQjlRMEpkLiP3kBZlGhVwFsM0i2VWFnCeul40yyYqS0uHJ0rmJRyrWEVlcQ5OWnee-XqcZ-BXrMoo8aazSRrJqVczireeYMJHlDBTBzXBLfMRF4hgRkjYEFoFNOS0MvSOtY0gDQ04d7MOAtb6hDmUnoEfh72Pffe0M3arN0tbm_W6ejDdzuqAcuz2CQdevAP_K9SYIs59yjBz1NWBqvvO2t60-rFfbqr-WWOkX_Trt_q106-P-l352_GL3d3GNK_Vg28Xe4d4abdm_5pW_b3mggpfJ4s_OkZ4nvu_b_U1_QftGItg</recordid><startdate>197611</startdate><enddate>197611</enddate><creator>ROTHMAN, KENNETH J.</creator><creator>FYLER, DONALD C.</creator><general>Oxford University Press</general><general>School of Hygiene and Public Health of the Johns Hopkins University</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HVZBN</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>7X8</scope></search><sort><creationdate>197611</creationdate><title>SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS</title><author>ROTHMAN, KENNETH J. ; FYLER, DONALD C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-74750324ec8c21f450670214229d23a83963ae3b4fd72d3866d72c884f5246703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Adult</topic><topic>aortic diseases</topic><topic>aortic valve stenosis</topic><topic>arterio-venous fistula</topic><topic>Birth Order</topic><topic>congenital</topic><topic>Ductus Arteriosus, Patent</topic><topic>Female</topic><topic>heart defects</topic><topic>Heart Defects, Congenital - epidemiology</topic><topic>Heart Septal Defects, Atrial</topic><topic>Humans</topic><topic>Male</topic><topic>Maternal Age</topic><topic>New England</topic><topic>Pregnancy</topic><topic>Sex Factors</topic><topic>Transposition of Great Vessels</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ROTHMAN, KENNETH J.</creatorcontrib><creatorcontrib>FYLER, DONALD C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Periodicals Index Online Segment 24</collection><collection>Periodicals Index Online</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - West</collection><collection>Primary Sources Access (Plan D) - International</collection><collection>Primary Sources Access &amp; Build (Plan A) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Midwest</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Northeast</collection><collection>Primary Sources Access (Plan D) - Southeast</collection><collection>Primary Sources Access (Plan D) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Southeast</collection><collection>Primary Sources Access (Plan D) - South Central</collection><collection>Primary Sources Access &amp; Build (Plan A) - UK / I</collection><collection>Primary Sources Access (Plan D) - Canada</collection><collection>Primary Sources Access (Plan D) - EMEALA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - South Central</collection><collection>Primary Sources Access &amp; Build (Plan A) - International</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - International</collection><collection>Primary Sources Access (Plan D) - West</collection><collection>Periodicals Index Online Segments 1-50</collection><collection>Primary Sources Access (Plan D) - APAC</collection><collection>Primary Sources Access (Plan D) - Midwest</collection><collection>Primary Sources Access (Plan D) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Canada</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - EMEALA</collection><collection>Primary Sources Access &amp; Build (Plan A) - APAC</collection><collection>Primary Sources Access &amp; Build (Plan A) - Canada</collection><collection>Primary Sources Access &amp; Build (Plan A) - West</collection><collection>Primary Sources Access &amp; Build (Plan A) - EMEALA</collection><collection>Primary Sources Access (Plan D) - Northeast</collection><collection>Primary Sources Access &amp; Build (Plan A) - Midwest</collection><collection>Primary Sources Access &amp; Build (Plan A) - North Central</collection><collection>Primary Sources Access &amp; Build (Plan A) - Northeast</collection><collection>Primary Sources Access &amp; Build (Plan A) - South Central</collection><collection>Primary Sources Access &amp; Build (Plan A) - Southeast</collection><collection>Primary Sources Access (Plan D) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - APAC</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - MEA</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ROTHMAN, KENNETH J.</au><au>FYLER, DONALD C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS</atitle><jtitle>American journal of epidemiology</jtitle><addtitle>Am J Epidemiol</addtitle><date>1976-11</date><risdate>1976</risdate><volume>104</volume><issue>5</issue><spage>527</spage><epage>534</epage><pages>527-534</pages><issn>0002-9262</issn><eissn>1476-6256</eissn><abstract>The records of the New England Regional Infant Cardiac Program, a service program covering all of New England, provide a useful source of information about the characteristics of children born with congenital heart defects. Data were analyzed on more than 2000 children born in New England who were diagnosed with a congenital heart defect before the first birthday. Children with arterio-venous fistula, aortic stenosis, transposition of the great arteries or hypoplastic left ventricle were predominantly male; children with persistent ductus arteriosus and endocardial cushion defect were predominantly female. Positive trends in risk with increasing birth order were present for pulmonic stenosis and transposition of the great arteries, and a negative trend was seen for persistent ductus arteriosus. What evidence there was for associations with maternal age was greatly reduced after controlling for confounding by birth order.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>984027</pmid><doi>10.1093/oxfordjournals.aje.a112326</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0002-9262
ispartof American journal of epidemiology, 1976-11, Vol.104 (5), p.527-534
issn 0002-9262
1476-6256
language eng
recordid cdi_proquest_miscellaneous_83612147
source Oxford University Press Archive
subjects Adult
aortic diseases
aortic valve stenosis
arterio-venous fistula
Birth Order
congenital
Ductus Arteriosus, Patent
Female
heart defects
Heart Defects, Congenital - epidemiology
Heart Septal Defects, Atrial
Humans
Male
Maternal Age
New England
Pregnancy
Sex Factors
Transposition of Great Vessels
title SEX, BIRTH ORDER, AND MATERNAL AGE CHARACTERISTICS OF INFANTS WITH CONGENITAL HEART DEFECTS
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A53%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=SEX,%20BIRTH%20ORDER,%20AND%20MATERNAL%20AGE%20CHARACTERISTICS%20OF%20INFANTS%20WITH%20CONGENITAL%20HEART%20DEFECTS&rft.jtitle=American%20journal%20of%20epidemiology&rft.au=ROTHMAN,%20KENNETH%20J.&rft.date=1976-11&rft.volume=104&rft.issue=5&rft.spage=527&rft.epage=534&rft.pages=527-534&rft.issn=0002-9262&rft.eissn=1476-6256&rft_id=info:doi/10.1093/oxfordjournals.aje.a112326&rft_dat=%3Cproquest_cross%3E1306653414%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c431t-74750324ec8c21f450670214229d23a83963ae3b4fd72d3866d72c884f5246703%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1306653414&rft_id=info:pmid/984027&rfr_iscdi=true