The nucleolar fibrillar centres in various cell types in vivo or in vitro

Nucleoli were studied in chick fibroblasts cultured in vitro, under normal or under experimental conditions, and in several mammalian cell types in vivo. All these cells frequently contain nucleoli with fibrillar centres. The nucleolar fibrillar centres are composed of fibrous material of low electr...

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Bibliographic Details
Published in:Cell and tissue research 1976-10, Vol.173 (3), p.315-324
Main Author: Goessens, G
Format: Article
Language:English
Subjects:
Animals
Carcinoma, Ehrlich Tumor - ultrastructure
Cell Nucleolus - analysis
Cell Nucleolus - ultrastructure
Chick Embryo
DNA - analysis
Mice
Microscopy, Electron
Rats
RNA - biosynthesis
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Summary:Nucleoli were studied in chick fibroblasts cultured in vitro, under normal or under experimental conditions, and in several mammalian cell types in vivo. All these cells frequently contain nucleoli with fibrillar centres. The nucleolar fibrillar centres are composed of fibrous material of low electron density and are always intimately associated with the dense fibrillar component. Their morphology is very similar to that analysed cytochemically in Ehrlich tumour cells. It therefore appears that they could be related to the nucleolar organizers as suggested in Ehrlich tumour cells.
ISSN:0302-766X
1432-0878
DOI:10.1007/BF00220319